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10 Best Liver Support for Dogs: Top Picks for 2025 to Keep Them Healthy
When it comes to our furry friends, ensuring they have a healthy liver is crucial for their overall well-being. The best liver support for dogs can significantly aid in maintaining liver health, preventing diseases, and ensuring a longer and healthier life. Pets, just like humans, can suffer from liver issues due to various factors including diet, age, and genetics. Fortunately, a variety of liver support supplements are available on Amazon that cater to different needs and preferences.
In this article, we’ll explore the top 10 liver support products for dogs that you can find on Amazon in 2025. Each review will include an in-depth analysis of features, pros, and cons, enabling you to make an informed decision for your beloved pet. Whether you are seeking supplements, treats, or herbal remedies, we’ve got you covered.
1. VetriScience Laboratories Liver Health Chews
VetriScience Laboratories Liver Health Chews
- Advanced Liver Support Formula: VetriScience Liver Health is a vet-formulated milk thistle liver supplement for dogs recommended to support liver health and function, promote healthy liver detoxification, and maintain normal liver enzyme levels
- Milk Thistle Supplement for Dogs: Powerful active ingredients like milk thistle, artichoke leaf extract, and turmeric support both liver and gallbladder function by supporting bile flow for healthy detox. Turmeric also offers anti-inflammatory properties for liver cell health
- Vitamins for Liver Health: Vitamins A, B, and E and folic acid provide antioxidant defense to fight free radicals and help protect the liver against normal damage
- SAMe Alternative Supplement: This milk thistle liver supplement for dogs is recommended for pets who, for any reason, cannot take SAMe supplements due to diet, complications, or medications
- Hydrolyzed Chicken Flavor: Liver support soft chews for dogs are made with a hydrolyzed chicken flavor that's appropriate for pets with sensitivities to chicken protein
Designed specifically for dogs, **VetriScience Laboratories Liver Health Chews** are delicious, peanut butter-flavored chews that help support liver function. They contain a blend of natural ingredients such as milk thistle and dandelion root, which are known for their liver-supportive properties. Each chew has been formulated to be palatable and easier for dogs to consume, making it an excellent option for picky eaters.
Pros:
- Tasty peanut butter flavor
- Contains natural ingredients like milk thistle
- Soft and chewy texture
- Easy to administer
Cons:
- Can be pricier compared to other options
- May not be suitable for dogs with specific allergies
2. Nutramax Denamarin Liver Support Supplement
Nutramax Denamarin Liver Support Supplement
- Liver Support for Dogs: Denamarin is the #1 veterinarian recommended liver support supplement for dogs. This supplement contains s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione - one of the liver’s main detoxifying agents
- High-Quality Ingredients: The Silybin found in Denamarin has shown better absorption by dogs than the standardized milk thistle extract found in many other products
- Support Your Dog's Liver Health: The liver is one of the most vital organs in your pet and is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system
- From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement
**Nutramax Denamarin Liver Support Supplement** is a top-rated product for liver health, combining S-adenosylmethionine (SAMe) and silybin. SAMe is crucial for liver detoxification and supports cellular health, while silybin promotes bile production. This supplement is available in different flavors to cater to your dog’s preferences and is especially effective for dogs with pre-existing liver conditions.
Pros:
- Features both SAMe and silybin for effective liver support
- Available in multiple flavors
- Clinically proven for liver health
Cons:
- Requires veterinarian approval for use
- Some dogs may resist the flavor
3. Pet Naturals of Vermont Liver Support Chews
Pet Naturals of Vermont Liver Support Chews
- WORKS IN 30 MINUTES - Pet Naturals Calming Chews for Dogs and Cats works in 30 minutes and is free of artificial ingredients than can cause upset tummies
- DELICIOUSLY FLAVORED - Calming soft chews are flavored with real chicken liver, so even the Pickiest pet will love it. Each bottle includes 160 chews
- TAKE AS NEEDED - Calming can be given every day or as needed and is safe to double or triple the dose in times of increased stress
- BEHAVIOR SUPPORT - Calming chews are recommended for pets that have issues with car rides, trips to the veterinarian, strangers, separation issues, storm stress and fireworks
- MADE IN THE USA - All Pet Naturals products are manufactured in the USA and distributed from our offices in the Green Mountains of Vermont
**Pet Naturals of Vermont Liver Support Chews** are formulated with natural ingredients that support liver function and detoxification. These chews come in a tasty chicken flavor and contain essential nutrients like taurine, vitamin E, and milk thistle, all contributing to liver health. They are gluten-free, making them a suitable option for dogs with dietary restrictions.
Pros:
- Tasty chicken flavor
- Gluten-free and made with natural ingredients
- Supports detoxification processes
Cons:
- Limited effectiveness without consistent use
- Some dogs may find them too chewy
4. Vet’s Best Comfort Fit Anti-Flatulence Dog Belly Bands
Vet’s Best Comfort Fit Anti-Flatulence Dog Belly Bands
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Though not a direct liver support product, the **Vet’s Best Comfort Fit Anti-Flatulence Dog Belly Bands** can help manage digestive issues, which indirectly benefits liver health. Designed to control flatulence, these bands are perfect for dogs with gastrointestinal discomfort, reducing stress on the liver. Made with soft, breathable materials, they are comfortable for daily wear.
Pros:
- Helps manage flatulence and bloating
- Comfortable, breathable fabric
- Adjustable design for a secure fit
Cons:
- Not directly related to liver support
- Can be cumbersome for active dogs
5. Zesty Paws Liver Support Bites
Zesty Paws Liver Support Bites
- For Healthy Liver Function – These pet chews also include Choline Bitartrate and Dandelion Root Powder to provide additional support for your dog's liver activity.
- Healthy Liver = Happy Life! – Zesty Paws Liver Support Bites are chewable supplements with ingredients that support canine liver health.
- Featuring Silactive – At 110 mg per chew, Silactive is a standardized form of Milk Thistle, an herbal extract with properties that support the liver's normal detoxifying process.
- Bad Liver? Here's What to Look For - If you notice weight changes, fatigue, bloating, vomiting, loose stool, or excessive thirst, your pup's liver might need some TLC. These chews may be able to help!
- Premium BioPerine – Each bite contains BioPerine, a premium black pepper extract that increases Curcumin absorption.
**Zesty Paws Liver Support Bites** are a tasty treat that offers more than just flavor. Packed with natural ingredients like milk thistle, these bites not only support liver health but also promote overall wellness. This product is great for dogs of all ages and can easily be incorporated into their daily routine.
Pros:
- Chewable and palatable
- Contains milk thistle for liver support
- Promotes overall health
Cons:
- Enhanced flavors may not be suitable for all dogs
- Requires multiple bites for noticeable effects
6. thera-cream Liver Aid for Dogs
thera-cream Liver Aid for Dogs
- 𝐋𝐈𝐕𝐄𝐑 𝐒𝐔𝐏𝐏𝐎𝐑𝐓 – Prana Pets Liver Supplement for pets helps address sluggish or slow liver function to aid in promoting healthy digestion in dogs and cats. Simply administer the recommended drops into their mouth or add it to their wet or dry food daily.
- 𝐍𝐀𝐓𝐔𝐑𝐀𝐋𝐋𝐘 𝐅𝐎𝐑𝐌𝐔𝐋𝐀𝐓𝐄𝐃 – Because Liver Supplement is comprised of tonic, adaptogenic herbs, it gently and safely helps improve liver function in pets to reduce indigestion caused by rich or fatty foods.
- 𝐑𝐄𝐃𝐔𝐂𝐄𝐃 𝐃𝐈𝐒𝐂𝐎𝐌𝐅𝐎𝐑𝐓 – Rather than just suppressing symptoms of liver dysfunction, our formula aids in relieving the symptoms such as abdominal pain and swelling, indigestion, and inflammation of the liver and gallbladder.
- 𝗣𝗥𝗔𝗡𝗔 𝗣𝗘𝗧𝗦 - Helps pets, and the people who love them, live their best lives through our holistic approach to health and wellness. Our best-in-class natural products and herbal remedies help alleviate common ailments in pets.
- 𝗦𝗔𝗙𝗘 – All our products are made in the USA and tested by an independent, third-party lab. You can buy with confidence that our products are safe for your pet.
The **thera-cream Liver Aid for Dogs** is a topical cream designed for liver support and recovery. Containing a blend of herbal ingredients, this cream can be applied to your dog’s skin to promote healing and detoxification. Its unique formulation provides an alternative approach to support liver health and can be especially useful for dogs recovering from illness.
Pros:
- Alternative to oral supplements
- Easy to apply
- Herbal formulation for natural support
Cons:
- Not suitable for all dogs
- May take longer to see results
7. Pet greens Co. Supplement for Liver Health
Pet greens Co. Supplement for Liver Health
- Award-Winning, Clinically Tested* Formula - ProBright Advanced is the dog dental care product of the year—now with a new flavor, superior ingredients, and a clinically tested formula. In just 28 days, daily use was shown to significantly reduce bad breath–causing compounds. Say goodbye to toothpaste, brushing battles, and dental sticks. Say hello to ProBright—advanced, effortless oral care at its best
- Target Tartar & Bad Breath – Tartar can cause bad breath and leave teeth stained & unsightly. This advance in canine dental care enables a hassle-free, thorough clean, leaving their mouth clean, fresh, and sparkling
- Easy To Use - Choose the right formula for your dog's size (Extra Small, Small, Medium, Large) and add one scoop using the scoop provided in the tub to their plate.
- Tailored To Your Pup – First select the right formula for your dog: Extra Small, Small, Medium, Large. ProBright XS includes a dual-ended scoop: use the little scoop for dogs under 4 lbs and the larger scoop for dogs 4–12 lbs—easy, accurate support made simple
- Manufactured in the USA - Our dog health supplies are manufactured in the USA using ingredients sourced from prime locations worldwide. As a NASC member, we meet the highest standards for pet supplements
**Pet greens Co. Supplement for Liver Health** offers a unique blend of greens designed to support liver detoxification. This supplement is rich in vitamins and minerals that enhance liver function and improve overall vitality. It is an easy powder formulation that can be mixed into your pet’s food.
Pros:
- High in natural vitamins and minerals
- Easy to mix with food
- Supports overall vitality
Cons:
- Some dogs may be reluctant to eat food mixed with powder
- Requires consistent use for best results
8. BARK Bright Pet Dental Chews for Liver Support
BARK Bright Pet Dental Chews for Liver Support
- Advanced Dental Care: Bark Bright Dental Sticks mimic a toothbrush with scrubbing ridges designed to help prevent plaque and tartar buildup. Includes chew sticks ONLY—Bark Bright Dental Kit with dog toothpaste sold separately on Amazon
- Thoughtfully Designed: Pronounced ridges on each dental stick massage gums and clean hard-to-reach spots as dogs chew, ensuring a thorough clean for fresher breath and cleaner teeth. No toothpaste included
- Irresistibly Delicious: Establish an easy dog dental care routine with thoughtfully-designed BARK dental chew sticks, made with real chicken to fight stinky dog breath. Your pup will be begging when it’s time for their daily teeth cleaning
- Expertly Formulated: Made with premium ingredients, Bright Dental Chew Sticks contain no artificial colors, flavors, or preservatives. Plus, there's no grain or corn fillers—only the best dental care treatment for your dog to live their best life
- No-Fuss Routine: Recommended as a once-daily teeth cleaning and breath freshening routine (chews only) for dogs who turn their nose up at toothbrushes. It’s as easy as one, chew, three
**BARK Bright Pet Dental Chews** offer a unique combination of dental support and liver health benefits. With natural ingredients that promote liver function, these chews engage your dog’s chewing instincts while simultaneously providing dental hygiene. The unique texture helps in cleaning teeth while enhancing liver health.
Pros:
- Dual purpose for dental and liver support
- Engaging for dogs
- Natural ingredients for safety
Cons:
- Not a complete substitute for regular dental care
- May not be suitable for small breeds
9. VetriScience Laboratories Canine Liver Support
VetriScience Laboratories Canine Liver Support
- Advanced Liver Support Formula: VetriScience Liver Health is a vet-formulated milk thistle liver supplement for dogs recommended to support liver health and function, promote healthy liver detoxification, and maintain normal liver enzyme levels
- Milk Thistle Supplement for Dogs: Powerful active ingredients like milk thistle, artichoke leaf extract, and turmeric support both liver and gallbladder function by supporting bile flow for healthy detox. Turmeric also offers anti-inflammatory properties for liver cell health
- Vitamins for Liver Health: Vitamins A, B, and E and folic acid provide antioxidant defense to fight free radicals and help protect the liver against normal damage
- SAMe Alternative Supplement: This milk thistle liver supplement for dogs is recommended for pets who, for any reason, cannot take SAMe supplements due to diet, complications, or medications
- Hydrolyzed Chicken Flavor: Liver support soft chews for dogs are made with a hydrolyzed chicken flavor that's appropriate for pets with sensitivities to chicken protein
**VetriScience Laboratories Canine Liver Support** is formulated with a mix of antioxidants and amino acids to help protect liver cells from damage and enhance liver function. These soft chews are not only effective but also come in a palatable form that dogs love. Ideal for regular maintenance of liver health, this product is backed by veterinary research.
Pros:
- Contains key antioxidants and amino acids
- Easy-to-chew format
- Research-backed effectiveness
Cons:
- May take time to show significant benefits
- Some dogs might prefer treats over supplements
10. NaturVet Milk Thistle Support for Dogs
NaturVet Milk Thistle Support for Dogs
- DOG HEALTH SUPPLEMENTS: Feel good about feeding your dog these pet health supplements that feature a blend of ginkgo biloba, lutein, milk thistle and coenzyme Q10 to support your dog’s overall health.
- DOG LIVER SUPPORT: This premium pet health supplement fuels your dog with antioxidants to help support eye health, liver and heart function and cognitive function in dogs. Each soft chew dog supplement features flavoring that tastes great.
- IDEAL PET SUPPLEMENT FOR DOG HEART HEALTH: Help encourage activity and comfort when feeding your canine companion this NaturVet Senior Advanced 5-in-1 Support Dog Supplement. This dog supplement works to help support the immune system, eye, heart and liver health.
- DOG IMMUNE SYSTEM SUPPORT HEALTH SUPPLEMENT: Help your furry friend boost his immune system, especially when aging, with this dog supplement that includes turkey tail mushroom, gingko biloba and lutein.
- PET PRODUCTS YOU CAN TRUST: Since 1994, NaturVet has been serving the four-legged community with wholesome, vitamin-infused dog supplements so that your pup or senior dog maintains a healthy lifestyle. Made in the USA, each pet product from NaturVet is cGMP compliant and wheat-free.
**NaturVet Milk Thistle Support for Dogs** utilizes the power of milk thistle, an herb known for its detoxifying properties, to provide unparalleled support for liver health. The capsules can be easily given as a treat or mixed in food. This product is particularly beneficial for older dogs or those with existing liver conditions as it promotes cell regeneration and toxin removal.
Pros:
- Contains high-quality milk thistle
- Great for older dogs or those in need of extra support
- Capsules allow for easy administration
Cons:
- Some dogs may reject capsules
- Needs proper dosage recommendations from a vet
These products represent some of the best liver support for dogs available on Amazon in 2025. Each product has its unique strengths and weaknesses, suitable for various lifestyles and preferences. Always consult with your veterinarian before introducing new supplements or treatments to ensure they match your pet’s specific needs.
Buying Guide for Liver Support for Dogs
Maintaining your dog’s liver health is crucial for overall well-being. The liver plays a significant role in detoxification, metabolism, and digestion. If you’re considering liver support for your canine companion, here’s a comprehensive guide to help you make an informed decision.
1. Consult Your Veterinarian
Before purchasing any liver support product, consult your veterinarian. They can assess your dog’s specific needs, conduct tests if necessary, and recommend appropriate treatment options based on your dog’s age, breed, size, and any existing health conditions.
2. Types of Liver Support Products
- Supplements: These often contain ingredients like milk thistle, SAM-e (S-adenosylmethionine), or antioxidants that support liver function.
- Prescription Medications: In cases of severe liver dysfunction, your veterinarian may prescribe medications specifically formulated for liver support.
- Dietary Changes: Specialized dog foods designed for liver health can provide the necessary nutrients to support liver function.
3. Key Ingredients to Look For
- Milk Thistle: Contains silymarin, known for its antioxidant properties and liver protection.
- SAM-e: Helps improve liver function and reduce liver damage.
- Antioxidants: Vitamins E and C, along with other antioxidants support the liver by reducing oxidative stress.
- Dietary Fiber: Promotes digestion and helps in detoxification.
- Omega Fatty Acids: Can help reduce inflammation and support overall health.
4. Formulation and Administration
- Chewable Tablets: Usually palatable and easy for dogs to ingest.
- Powders: Can be mixed with food but may require careful measurement for dosing.
- Liquids: Easy to administer but may not always be as potent as pills or powders.
- Treats: Some liver support comes in the form of treats, appealing to dogs and making administration easier.
5. Quality and Safety
- Third-party Testing: Look for products that have been tested by independent laboratories to ensure purity and potency.
- Brand Reputation: Choose products from reputable brands with positive reviews and a history of quality.
- Avoid Fillers: Seek supplements that don’t contain artificial colors, flavors, or unnecessary fillers.
6. Dosage and Administration
Follow the manufacturer’s recommended dosage guidelines carefully, and adjust based on your vet’s advice. Monitor your dog for any adverse reactions, and keep your vet informed of any changes.
7. Cost Considerations
The price of liver support products can vary widely. Consider long-term value and the importance of quality over cost. Some premium products may provide better health benefits and value in the long run.
8. Monitoring Liver Health
Keep track of your dog’s liver health with regular veterinary check-ups and blood tests. These can help in assessing liver function and the effectiveness of the liver support regimen you choose.
9. Lifestyle Factors
In addition to supplements and dietary changes, consider lifestyle factors that can support liver health, including:
- Regular exercise
- A balanced diet
- Maintaining a healthy weight
- Minimizing exposure to toxins (e.g., chemicals, certain foods)
Conclusion
Supporting your dog’s liver health is an investment in their overall quality of life. By understanding the options available and consulting with a veterinarian, you can choose the best liver support products tailored to your dog’s unique needs. Always remember that a proactive approach is key to ensuring your dog’s long-term health and happiness.
