The search for the best neutral detergent can lead you to countless options, particularly on a platform as expansive as Amazon. In 2025, a variety of neutral detergents have emerged as frontrunners, thanks to their effectiveness, safety, and versatility for a range of cleaning tasks. Whether you aim to clean your delicate fabrics or sanitize various surfaces, choosing the best neutral detergent can make all the difference.
Neutral detergents tend to be milder than their alkaline counterparts, making them suitable for use on a range of materials without causing any damage. This article reviews the top 10 neutral detergents available on Amazon, revealing their features, pros, and cons to help you make an informed decision.
1. Arm & Hammer Sensitive Skin Free & Clear Laundry Detergent
Arm & Hammer Sensitive Skin Free & Clear Laundry Detergent
Arm & Hammer’s Sensitive Skin Free & Clear Laundry Detergent is designed for those with sensitive skin and allergies. It eliminates tough stains while being free from dyes and perfumes. The baking soda formula helps neutralize odors, leaving your clothes fresh and clean.
Features: Free from harsh chemicals, hypoallergenic, concentrated formula, and effective in cold water.
Pros: Excellent for sensitive skin, environmentally friendly, and effective stain removal.
Cons: Some users may find the cleaning performance less effective on very tough stains.
No products found.
2. Tide Free & Gentle Liquid Laundry Detergent
Tide Free & Gentle Liquid Laundry Detergent
Tide Free & Gentle Liquid Laundry Detergent is another popular choice known for its high-performance cleaning ability without the harsh chemicals that irritate sensitive skin. Formulated with a unique blend, it effectively fights against stains while providing a gentle wash for all your fabrics.
Features: Free of perfumes and dyes, dermatologist tested, and safe for septic systems.
Pros: Versatile for all washing machines, ensures bright colors, and effective stain removal.
Cons: A bit pricier compared to standard detergents.
- DEEP CLEAN: For a deep clean that's gentle on skin. Removes more stains than the leading Free detergent
- Free from dyes and perfumes for a laundry detergent that's gentle on your skin and clothes
- Hypoallergenic laundry detergent that's specially formulated to minimize the risk of skin irritation and allergies
- No matter what type of machine you have or the water temperature you prefer, Tide Free & Gentle ensures exceptional cleaning results every time
- Safe to use on all fabric types
3. Seventh Generation Free & Clear Laundry Detergent
Seventh Generation Free & Clear Laundry Detergent
Seventh Generation’s Free & Clear Laundry Detergent is a plant-based product that combines effectiveness with environmental responsibility. This detergent provides a powerful clean without synthetic fragrances, dyes, or artificial brighteners, making it ideal for eco-conscious consumers.
Features: Biodegradable formula, certified cruelty-free, and concentrated for more washes.
Pros: Gentle on sensitive skin, environmentally sustainable, and great cleaning performance.
Cons: May require more detergent for larger loads.
- Seventh Generation Free & Clear Concentrated Laundry Detergent Fragrance-Free has a powerful triple-enzyme formula fights tough stains
- Free & Clear hypoallergenic laundry detergent made for sensitive skin
- A laundry detergent that is EPA Safer Choice Certified and designed with safety in mind
- Concentrated detergent washes 53 medium loads in high-efficiency (HE detergent) or standard machine
- USDA Certified 96 percent Biobased laundry detergent liquid made with plant-based ingredients
4. Persil ProClean Sensitive Skin Liquid Laundry Detergent
Persil ProClean Sensitive Skin Liquid Laundry Detergent
Persil ProClean Sensitive Skin Liquid is known for its powerful cleaning capabilities while being dermatologically tested for safety. This formula works great in both standard and high-efficiency washers, delivering excellent stain removal without compromising skin health.
Features: Free of dyes and perfumes, highly concentrated, and works in all water temperatures.
Pros: Deep clean on stubborn stains, safe for sensitive skin, and good value for money.
Cons: The packaging can be awkward for pouring.
No products found.
5. All Free Clear Liquid Laundry Detergent
All Free Clear Liquid Laundry Detergent
All Free Clear is designed specifically for families with allergic skin types, offering a powerful clean without any added fragrances or dyes. Recommended by dermatologists, this detergent is effective in removing tough stains while maintaining the integrity of fabrics.
Features: Safe for sensitive skin, effective stain lifter, and works in all water temperatures.
Pros: Affordable price point, good for allergens, and compatible with HE machines.
Cons: Some users have noted a lack of freshness in scent.
−$2.99
- all free clear is the #1 laundry detergent brand recommended by dermatologists, allergists and pediatricians for sensitive skin.100% free of perfumes and dyes, all free clear liquid laundry detergent provides an effective clean that's gentle on skin
- Now more concentrated. More cleaning power per drop* *vs previous 1.5oz dose formula. Removes impurities without leaving irritating residues** **Like dirt, body oil and allergens
- Use with all free clear fabric softener and dryer sheets for clean and soft clothes with static cling reduction in the dryer
- all free clear Original is Safer Choice certified which means it’s been recognized by the United States Environmental Protections Agency (EPA) to be better for you, your family and the planet
- all free clear Original includes biodegradable surfactants. Safe for septic systems. Works effectively, even in cold water. As always, contains no phosphates. Safe for all HE washing machines. - Includes one 82.5oz bottle, enough for 110 loads
6. ECOS Laundry Detergent
ECOS Laundry Detergent
ECOS Laundry Detergent is plant-powered and completely free from harmful chemicals. It’s a biodegradable option that’s gentle on fabrics and tough on stains. This detergent comes in various scents, including a fragrance-free version for sensitive users.
Features: Made with natural ingredients, vegan and cruelty-free, and highly concentrated for efficiency.
Pros: Eco-friendly, hypoallergenic, and competitively priced.
Cons: The scent can be too strong for some users.
- CLIMATE POSITIVE AND SUSTAINABLE - Not only is this laundry detergent formula effective and kind to sensitive skin, but it's also pH-balanced.
- 100% VEGAN – Containing enough detergent for 200 loads of laundry, plant-powered ECOS Laundry Detergent is both cruelty-free and vegan, making it an ideal choice for planet-conscious households.
- PARABEN AND PHOSPHATE FREE - Unlike most conventional laundry detergents, ECOS does not contain any harsh chemicals or ingredients that can pollute water when it enters the ecosystem.
- DERMATOLOGIST-TESTED AND HYPOALLERGENIC - ECOS Laundry Detergent is an effective yet gentle cleaning solution for clothes that is suitable for families with skin allergies and sensitivities.
- MADE IN USA - Proudly made in the USA with globally sourced ingredients
7. Charlie’s Soap Laundry Powder
Charlie’s Soap Laundry Powder
Charlie’s Soap Laundry Powder offers a unique formula that provides a powerful clean with minimal ingredients. This detergent is free of fragrances, dyes, and fillers, making it an excellent option for sensitive individuals and families.
Features: Biodegradable, non-toxic, and works in all types of washing machines.
Pros: Highly concentrated, effective in removing odors, and environmentally sound.
Cons: Requires precise measuring for optimal results.
−$2.58
- ECO-FRIENDLY CLEANING POWER: New Convenient 150 load size concentrated powdered laundry soap works on all your laundry, from high-tech fabrics to delicates, washing away smells, stains, and left-behind residue from previous detergents.
- HYPOALLERGENIC: Washing soda and powerful, natural ingredients work together to deep clean, rinse from fabrics completely, and leave nothing on your clothes. The fragrance-free formula is ideal for those with sensitive skin and will not cover stains or odors with artificial brighteners or perfumes. Our powder laundry detergent is safe for hand washing.
- CLOTH DIAPER FRIENDLY: This detergent is safe to use on baby fabrics, effectively deep cleaning cloth diapers and other baby clothes between wears perfect along with your other baby essentials.
- LESS IS MORE: Each bag contains just four ingredients and one tablespoon per dose. No suds, just a deep clean that leaves fabric fresh and soft and your washing machine cleaner by removing old laundry detergents left deep in your machine.
- EPA SAFER CHOICE CERTIFIED: Charlie’s Soap laundry soap and our other sustainable products are certified safer for the environment and is septic safe. The eco-friendly formula helps remove fats, oils, greases, and odors from sewer lines, saving your town money and water making it the perfect laundry solution.
8. Biokleen Laundry Liquid
Biokleen Laundry Liquid
Biokleen’s Laundry Liquid features a plant-based formula that effectively tackles stains and odors while being gentle on fabrics. It’s free of harsh chemicals and fragrances, making it ideal for sensitive skin and environmentally-conscious users.
Features: Non-toxic, concentrated, and effective even in cold water.
Pros: Great for a variety of fabrics, encourages pollution reduction, and cruelty-free.
Cons: Higher price point compared to standard detergents.
- PLANT-BASED LAUNDRY DETERGENT: Biokleen uses plant-derived cleaning agents to eliminate tough stains and odors, leaving your clothes crisp and fresh.
- HYPOALLERGENIC FORMULA: Biokleen Free & Clear uses a hypoallergenic formula that works great in High Efficiency and standard washers, and is gentle on sensitive skin.
- ULTRA-CONCENTRATED: Biokleen laundry products are 3X concentrated to reduce packaging, waste and energy.
- NO HARSH INGREDIENTS: Biokleen liquid laundry soaps are plant-based, eco-friendly solutions with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
- MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts
9. Mrs. Meyer’s Clean Day Laundry Detergent
Mrs. Meyer’s Clean Day Laundry Detergent
Mrs. Meyer’s Clean Day Laundry Detergent is known for its delightful scents derived from essential oils while being effective for cleaning clothes. This product is formulated with plant-derived ingredients to ensure a powerful clean without harsh chemicals.
Features: Available in various scents, made with plant-derived ingredients, and cruelty-free.
Pros: Pleasant aroma, gentle on fabrics, and effective stain removal.
Cons: Some scents may not be suitable for those with allergies.
−$4.48
- Concentrated detergent formula is effective yet gentle on clothes
- Contains plant-derived cleaning agents with dirt, stain-fighting enzymes, and other thoughtfully chosen ingredients
- 64 loads of laundry per bottle
- Biodegradable formula, HE laundry detergent for use in high efficiency and conventional washing machines
- Rain Water scented laundry detergent has a fragrance so clean. Drops of Rain Water fall on leaves and noses and fill the air
10. Method Laundry Detergent
Method Laundry Detergent
Method Laundry Detergent combines eco-friendliness with effectiveness, offering a concentrated formula that tackles tough stains. This detergent is formulated to work well in both cold and hot water while keeping your clothes fresh through pleasant scents.
Features: Plant-based, non-toxic, and comes in various scents.
Pros: Eco-friendly, effective cleaning power, and pleasant fragrances.
Cons: Some users feel the cleaning could be more robust on heavily soiled items.
- Concentrated Laundry Detergent, Ginger Mango.- in a small & stylish 1.58 liter, 100% recycled bottle with enough for 66 loads. your clothes will thank you!
- Tough on dirt and stains for the and standard machines.
- Keeps color bright and whites white.
- Naturally derived, plant based biodegradable and hypoallergenic formula.
- Transparent recyclable bottle is made with 100% PCR (post consumer recycled) materials.
With the variety of neutral detergents available on Amazon, you can choose the one that fits your lifestyle, preferences, and cleaning needs. The best neutral detergent will not just clean effectively but also cater to sensitive skin and eco-friendly requirements, ensuring a safe and pleasant laundering experience.
Buying Guide for Neutral Detergent
Neutral detergents are versatile cleaning agents that are pH-balanced, making them suitable for various surfaces and materials. When looking to purchase neutral detergent, consider the following factors:
1. Understand Your Needs
- Application Area: Determine where you will be using the detergent (e.g., on fabrics, hard surfaces, or for industrial cleaning).
- Specific Surfaces: Ensure that the detergent is suitable for the materials you’ll be cleaning (e.g., wood, tile, glass, delicate fabrics).
2. pH Level
- Neutral pH: Look for detergents with a pH level around 7. This ensures that it won’t damage sensitive surfaces or leave behind residues.
3. Ingredients
- Eco-Friendly Options: If sustainability is important to you, check for biodegradable ingredients and those that are free from harsh chemicals.
- Additives: Some detergents come with additional agents such as anti-static or optical brighteners. Determine if these features are beneficial for your cleaning tasks.
4. Concentration
- Concentrated vs. Regular: Concentrated neutral detergents may be more cost-effective over time, requiring less product per use.
- Dilution Guidelines: Ensure clear instructions for dilution if purchasing concentrated formulas.
5. Packaging Size
- Volume: Consider how much product you realistically need. Larger containers may save money but ensure you have the storage space.
- Convenience: Containers with dispensers or easy-pour spouts can make usage more convenient.
6. Brand Reputation
- Research Brands: Look for trusted brands with positive reviews concerning effectiveness, safety, and quality.
- Certifications: Check for certifications indicating safety and environmental standards.
7. Price
- Compare Costs: Prices can vary widely. Compare unit costs (price per ounce or liter) to find the best value.
- Bulk Purchasing: If you use neutral detergent frequently, consider buying in bulk for savings.
8. Usage Instructions
- Read the Label: Ensure the product has clear instructions for use, including recommended applications and any cautionary notes.
9. Safety
- Non-Toxic: If you have children or pets, prioritize non-toxic and safe formulations.
- Skin Sensitivity: Consider if you or anyone using the detergent has skin allergies and check product safety warnings accordingly.
10. Customer Reviews
- Explore Feedback: Look at customer reviews to gauge effectiveness and user satisfaction. Positive testimonials can be a good indicator of quality.
Conclusion
When choosing a neutral detergent, consider the above factors to ensure that you select a product that meets your cleaning needs while being safe for surfaces and the environment. Conduct research, compare options, and make an informed decision to find the best detergent for your specific requirements.