The fifth season of Big Mouth will be available on Netflix on November 5. John Mulaney, Nick Kroll, and Jessi Klein are among these crudely funny animated sitcom cast members. In anticipation of the upcoming release of Big Mouth season 5, we’ve compiled the most critical details from season 4 and a summary of the season’s conclusion.
Summer Camp for Nick, Andrew, and Jessi
Season 5 of Big Mouth continued up just where Season 4 left off, with Nick, Andrew, and Jessi wrapping up their seventh-grade year and traveling to Camp Mohegan Sun for the summer. When Nick’s longstanding camp buddy Seth Goldberg meets Andrew, the tension between Nick and Andrew heats up (voiced by Seth Rogen).
Natalie (voiced by Josie Totah), who is transgender and just came out, becomes Jessi’s best friend as she tries to learn how to insert a tampon. The summer’s conclusion finds Nick and Andrew rekindling their relationship when Andrew’s acute constipation ties them together.
With time, Missy learns to accept and love who she is (with a new voice actor)
While Missy Foreman-Greenwald (Ayo Edebiri and Jenny Slate) has always been half-Black and half-Jewish, she learns more about Black culture in Season 4. That, and Missy learns more about embracing her uniqueness so that she may express herself more clearly. As a result, actress Jenny Slate stepped aside from playing Missy to allow a Black actress to take the role.
In Season 4, Episodes 9 and 10, Ayo Edebiri takes over the role of Missy as the new voice of the character. Also, Missy has ditched her trademark overalls and headband appearance for a more adult dress and sleek braids.

Meanwhile, Jason Mantzoukas and Nick Kroll’s Lola Skumpy and Jay Bilzerian (Jason Mantzoukas) are the season’s prettiest pair. Matthew MacDell (Andrew Rannells) helped Jay recognize that he wasn’t straight earlier in the series. Finally, he was able to tell his father about his sexuality. After all, he had to tell his mother the truth.
Outsiders would think Big Mouth is a wildly insane program, and that evaluation is partly correct. On the other hand, Big Mouth addresses a wide range of subjects in a manner that doesn’t appear preachy or forced. On November 5, Netflix will debut Season 5.
The arrival of Tito, the Anxiety Mosquito
When Nick is nervous about being left out of Seth and Andrew’s growing relationship, he encounters Tito the Anxiety Mosquito during summer camp. Anxiety Mosquito appears to both Andrew and Jessi at several points in Season 5, often with its co-worker, the Depression Kitty.

Lola and Jay go on a date (And Break Up)
Jay and Lola are both repulsive and tender at the beginning of their relationship. Lola teaches Jay how to finger him in one of their most beautiful moments, as he lets her lead the way and prioritizes his wishes for her. They split up towards the conclusion of season one after Jay tells Lola that he loves her, and she cannot respond immediately. This, of course, leads to a declaration of war.
New characters make their debut in the fourth season of Big Mouth
The program is noted for its lightheartedness and willingness to tackle complex, often uncomfortable themes. This season is no exception, with a slew of new characters joining the cast to carry on the show’s spirit that has made it so famous.
Tito the Anxiety Mosquito (voiced by Maria Bamford), a camp counselor called Harry (voiced by John Oliver), and Seth Goldman (voiced by Seth Rogen) make up this season’s ensemble of characters.
Big Mouth Season 4 Ending
Andrew struggles with obsessive-compulsive disorder and a paralyzing dread of death that only worsens, while Nick isolates himself to shield himself from his mounting anxiety. It is only after her parents learn that she has been skipping school that they bring her back to Bridgeton so that she may attend the same school that she had been attending before.
When Jay tells Lola he loves her, he’s devastated when she doesn’t instantly respond with her declaration of love. It seems likely that the conflict will continue until the fifth season. Every year on October 31, a sorority party brings together all of the school’s students to confront their demons. Except for Nick, whose spirit is relocated when his evil alter-ego takes over his body, they all find some serenity.
Through their assistance, Nick can take back his body and eliminate the terrible alter-ego haunting him for so long. “The healing power of appreciation” is one lesson that Gratitoad imparts to the group. To put it simply, being thankful for the things and people in your life is a powerful antidote to your stress.