With both doses, the efficacy of Sputnik V against the Delta variant is greater than 90%

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Researcher Denis Logunov, deputy director of the Gamaleya Research Center and developer of the Sputnik V, today assured that its efficacy against Delta variant of coronavirus “Is greater than 90%”, since the Russian vaccine “shows a smaller decrease in efficacy against this variant than any other.”

“Dr. Denis Logunov, Sputnik V Developer: Efficacy of Sputnik V against Delta variant is greater than 90% as Sputnik V shows less decrease in efficacy against Delta than any other vaccine that has published efficacy results for Delta variant ”Posted the Sputnik Twitter account.

During a press conference this morning, Logunov explained that developers are guided by data from the Umias (Uniform Medical Information and Analytical System) and Egisz (Project Unified State Health Information System) systems, which collect information in a comprehensive manner. of the health system.

“According to this information, even with respect to the Indian strain (Delta variant that originated in that country), the effectiveness of the Sputnik vaccine is still around 90%,” Logunov said at the conference, according to the news agency. russian Rossiya Segodnya.

Sources from the Russian Direct Investment Fund (RDIF) explained to the agency Telam that “the activity of neutralizing antibodies against the coronavirus spike protein and the efficacy of the vaccine are different indicators.”

“A decrease in serum efficacy is not equal to a decrease in the overall efficacy of the vaccine,” Logunov noted.

From the RDIF they described that in the case of Sputnik V, “a 2.6-fold decrease in the activity of neutralizing antibodies leads to a negligible drop in efficiencyas it remains at the 90% level, which is higher than for many existing coronavirus vaccines. This level ensures protection against the Delta strain ”.

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And they noted that this “works similarly for other vaccines, for example, after a 5.8-fold drop in neutralizing antibody activity, the efficacy of the Pfizer vaccine remained at about 90%.”

What is the Delta strain

The Delta strain corresponds to the B.1.617.2, which originated in India. The World Health Organization (WHO) decided to rename the names of the SARS-CoV-2 variants with Greek letters for a more correct international identification, with names “easy to pronounce and remember”. It is also about avoiding “stigmatizing and discriminatory” names for the countries and territories where they appeared.

This strain, which already in 85 countries, is the more contagious of all the coronavirus variants identified so far, according to the World Health Organization (WHO).

According to the British authorities, the Delta variant is 60% more contagious than the Alpha (British) variant. Recent studies revealed that it currently accounts for 96% of coronavirus cases in the UK and 20% of cases in France.

The variant Delta expands around the world leaving a record of infections in St. Petersburg, the second Russian city, and caused a return of restrictions even in countries that seemed to have left the health crisis behind such as Israel or Australia.

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