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10 Best Over the Counter Ear Infection Medicine for Dogs in 2025
As pet parents, we always want the best for our furry companions, especially when it comes to their health. One of the most common ailments affecting dogs is ear infections, which can lead to discomfort and pain if not treated promptly. Fortunately, there are many effective over-the-counter options available that can help relieve symptoms and treat infections. In this article, we will explore the best over the counter ear infection medicine for dogs available on Amazon in 2025.
1. Vet’s Best Ear Relief Wash for Dogs
This Vet’s Best Ear Relief Wash is crafted from a blend of natural ingredients, including aloe and witch hazel, designed to soothe your dog’s ears while effectively cleaning away dirt and debris.
With its gentle, non-irritating formula, this ear wash not only helps in preventing further ear infections but can also provide immediate relief from discomfort.
Best for: Immediate comfort and cleaning.
Pros:
- Contains natural ingredients.
- Soothes and cleans the ear.
- Easy to apply.
Cons:
- May take several applications for severe infections.
- The scent may be off-putting to some pets.
−$1.85
- IMMEDIATE RELIEF - Vet's Best Ear Relief Wash Cleaner for Dogs cleans and soothes raw, itchy, smelly, or greasy dog ears.
- NATURAL INGREDIENTS - Vet’s Best Ear Relief Wash uses a carefully formulated combination of natural ingredients, including witch hazel, chamomile, aloe vera, clove oil, and tea tree oil to help control unpleasant odor and itching.
- AS NEEDED - May be used daily or as needed to clean ears and control wax build-up.
- TOTAL CARE - Vet's Best Ear Relief Wash Cleaner is part of our complete treatment system for raw, itchy, and smelly dog ears. Use with Vet’s Best Dry Ear Relief.
- MADE IN THE USA - Alcohol-free and non-stinging. Used to refill the Vet's Best 4 oz ear cleaner wash.
2. Pet MD Dog Ear Cleaner Wipes
These Pet MD Dog Ear Cleaner Wipes provide a convenient way to maintain your dog’s ear health. Formulated with a gentle pH-balanced solution, these wipes are ideal for regular cleaning and can help prevent ear infections.
The handy wipes can easily remove wax buildup and debris, making ear care easier for both you and your pet.
Best for: Regular maintenance and cleaning.
Pros:
- Convenient and easy to use.
- Prevents wax buildup.
- Pleasant scent.
Cons:
- Not a standalone treatment for existing infections.
- May not reach deeper parts of the ear.
- Advanced Formulation Designed to Gently Clean, Deodorize and Dry Your Pets Ears
- Gentle and Safe for Regular Use which Prevents Ear Infections, Reduces Wax Build Up and Removes Debris in and Around the Ear
- 100 Convenient, Soothing and Non-Irritating Disposable Ear Wipes for Dogs. For Dogs Over 12 Weeks Old
- Reduce Foul Ear Odor and Prevents Infection to Keeps Your Dog Happy and Healthy without Medication
- Made in the USA in Federally Regulated Manufacturing Facilities to Ensure Quality and Safety
3. Zymox Ear Solution with Hydrocortisone
Zymox is well-known for its effective formulas, and their ear solution with hydrocortisone is no exception. This product uses a unique enzyme formulation to help fight infections and soothe inflammation.
The hydrocortisone component adds an extra layer of relief from itching, making it particularly helpful for dogs experiencing acute discomfort.
Best for: Fighting infections and reducing inflammation.
Pros:
- Contains hydrocortisone for immediate relief.
- Works well for severe cases.
- Effective enzymatic formulation.
Cons:
- Should be used with caution; consult your vet first.
- Not suitable for long-term use.
- Cat and dog ear cleaner, soothes recurrent ear issues, itching and redness, for pets of all ages
- Relief from stubborn ear problem-causing microorganisms that form complex, irritating biofilms
- Gentle formula helps relieve painful ear issues caused by resistant germs, fungi and yeast
- Pet ear solution, no pre-cleaning of painful ears needed; safe, natural alternative to medication
- LP3 Enzyme System to help clear ear exudate; 1% Hydrocortisone for itchy ears
4. NaturPet Ear Cleaner for Dogs
NaturPet offers a natural solution with their Ear Cleaner for Dogs, which is suitable for both cleaning and soothing irritated ears. This holistic formula targets bacteria and fungi while maintaining a healthy environment in your dog’s ear canals.
The blend of essential oils and herbal extracts is not only effective but also safe for frequent use.
Best for: Natural treatment and prevention.
Pros:
- Natural ingredients.
- Safe for regular use.
- Reduces odors and cleans effectively.
Cons:
- May not be as effective for severe infections.
- Results may vary by dog.
- HELPS ALLEVIATE – This dog and cat ear cleaner was formulated with properties to help promote healthy ear canals. Rinse pet's ears daily with solution and massage area.
- DAILY MAINTENANCE – Helps breakdown buildup in the canal that may be causing foul odors and itching, scratching, and head shaking. Excellent for daily care and
- GENTLE FOR SENSITIVE EARS – Alcohol-free, mildly scented, and a non-irritating formula, this cat and dog ear wash is suitable for sensitive ears and gentle enough for frequent use.
- FOR YOUR PETS – Clinical Care Ear Therapy is great for dogs, cats, and small animals over 12 weeks for daily care and to maintain the ear health of your pet.
- EFFECTIVE & AFFORDABLE – Our premium products are high-quality at an affordable price. Store original container in a cool, dry place away from the sun, below 86°F or 30°C.
5. Vet’s Best Ear Relief Drops
The Vet’s Best Ear Relief Drops provide targeted relief for ear infections and discomfort. Formulated with a blend of natural ingredients, these drops help combat itching and irritation caused by infections.
This product is optimized for quick absorption, ensuring that your dog’s ears receive immediate treatment where it’s needed the most.
Best for: Targeted treatment for existing infections.
Pros:
- Quick-acting formula.
- Can be used for both cleaning and treating infections.
- Made from natural ingredients.
Cons:
- Requires consistent application for best results.
- Not suitable for long-term use.
- Vet's Best Dry Dog Ear Relief keeps your dog's ears fresh and dry, while helping to soothe raw, irritated, or greasy ears
- Naturally formulated to keep ear canals dry and provide itch relief for dog ear care
- Ear relief dry alcohol-free and stinging-free liquid turns from cream to a soft powder when dry
- Promotes clean ears after bathing or swimming
- To best support a healthy ear canal use in conjunction with Vet's Best Dog Ear Relief Wash
6. Colloidal Silver Dog Ear Drops
Colloidal Silver has gained fame in the pet health community for its antibacterial and anti-inflammatory properties. These ear drops provide a natural option for treating ear infections in dogs, delivering fast results without harsh chemicals.
The drops can easily penetrate earwax and debris, targeting infections at their source.
Best for: Natural antibacterial treatment.
Pros:
- Natural and chemical-free.
- Quick relief from discomfort.
- Reduces inflammation and promotes healing.
Cons:
- May not be suitable for all dogs; consult your vet first.
- Results can vary based on the severity of the infection.
- MEDICATED VET STRENGTH EAR DROPS - Fast-acting dog ear infection treatment drops made with pure elemental silver, 0.2% MicroSilver BG to provide antimicrobial defense against bacteria and yeast infections, and 1% Hydrocortisone to target itching and discomfort caused by inflammation.
- ALLERGY EAR DROPS FOR DOGS - Medicated dog ear cleaner drops made with 1% Hydrocortisone to target itching, redness, and inflammation. Oticbliss Ear Drops also contain Chitosan, a natural soothing and regenerative agent that supports your pet's comfort.
- SUPPORT HEALTHY CAT & DOG EARS - Oticbliss dog and cat ear cleaner and medicated drops help to maintain your pet's overall ear health & hygiene while targeting the effects of new or persistent ear symptoms in dogs and cats.
- VET FORMULATED & RECOMMENDED - Vetnique cat & dog pet supplies are made in the USA from globally sourced ingredients & recommended by veterinarians worldwide! Be sure to check out our store page for more high-quality pet products.
- VET FOUNDED. VET FORMULATED. VET RECOMMENDED - Vetnique products are made in the USA and recommended by veterinarians worldwide! Be sure to check out our store page for more high quality pet products.
7. VetIQ Ear Cleanser with Aloe
VetIQ’s Ear Cleanser features aloe to soothe irritated ears while also effectively cleaning them. This product is designed to remove wax buildup and debris, helping to maintain ear health.
The pH-balanced formula makes it a safe option for dogs of all ages, ensuring it can be used regularly without irritation.
Best for: Gentle and safe regular cleaning.
Pros:
- Soothes while it cleans.
- Ideal for routine maintenance.
- Safe for frequent use.
Cons:
- Less effective for existing infections.
- Requires consistent usage for optimal results.
- Effective Ear Cleanser: Formulated to cleanse and deodorize, maintaining fresh-smelling, healthy ears in dogs and cats.
- Supports Ear Health: Acidifies and dries the ear canal to promote a balanced ear environment, reducing moisture-related discomfort.
- Gentle Ingredients: Contains aloe vera and salicylic acid, providing a mild cleansing solution ideal for pets with sensitive ears.
- Ideal for Routine Care: Perfect for regular ear maintenance, especially after swimming or other activities that may trap moisture.
- Refreshing Cucumber Melon Scent: Leaves a pleasant fragrance, making ear care a more enjoyable experience for pets and owners.
8. Vet’s Best Seasonal Allergy Relief
For dogs suffering from ear infections due to allergies, Vet’s Best Seasonal Allergy Relief can be a key player. This product aims to alleviate itching caused by allergens, which can frequently lead to ear issues.
While not specifically an ear medicine, its anti-itch properties can help reduce the likelihood of secondary ear infections due to scratching and irritation.
Best for: Allergy-related ear infections.
Pros:
- Alleviates symptoms of allergies.
- Pleasant scent.
- Combines well with other ear treatments.
Cons:
- Not a direct treatment for infections.
- May require a vet’s consultation.
−$4.51
- BEST ITCHY SKIN RELIEF FOR DOGS: Vet’s Best Seasonal Allergy Supplements support dogs with seasonal allergy discomfort by promoting healthy skin moisture and maintaining normal histamine levels—helping soothe itching and improve skin comfort naturally.
- VET-FORMULATED ITCHY SKIN TREATMENT FOR DOGS: Created by veterinarians, this soothing formula combines plant-based ingredients like nettle leaf, perilla seed, and Vitamin E to calm itchy skin and support your dog’s skin health naturally and effectively.
- DOG ALLERGY RELIEF CHEWABLE TABLETS: These tasty chewable tablets are easy to give directly or mixed with your dog’s meal. Designed for convenience and palatability, they help support your dog’s allergy relief with a flavor they’ll love.
- PET PARENT APPROVED: Dog allergy relief infused with ocean kelp to support nutrient absorption, healthy digestion, and a strong immune response—helping your furry friend feel comfortable and balanced every day with natural, gentle care you can trust.
- QUALITY YOU CAN TRUST: Every bottle features the National Animal Supplement Council (NASC) Seal of Approval, reflecting our commitment to product quality, safety, and transparency so you can feel confident in what you're giving your animals.
9. TropiClean Ear Cleaner for Dogs
TropiClean offers a specialized ear cleaner formulated with natural ingredients to promote ear health and prevent infections. This product effectively removes wax and other debris while soothing the ear canal.
The blend of ingredients is also known for its fresh scent, making the cleaning process more pleasant for both you and your dog.
Best for: Freshening and cleaning ears.
Pros:
- Natural and effective formula.
- Fresh scent.
- Gentle enough for sensitive dogs.
Cons:
- Not effective for already established infections.
- Frequent usage is required for maintenance.
- GENTLE EAR DROPS – Our cat & dog ear wash provides a gentle clean with a cocoa butter scent by removing wax, debris, odor and itching.
- EASY-TO-USE – Fill their ear canal with the dog & cat ear cleaner and gently massage into ears. Wipe clean with a cotton ball.
- FEEL-GOOD INGREDIENTS – Alcohol-free dog ear wash cleaner is derived from natural ingredients such as cocoa butter & oats to soothe & moisturize dry, itchy skin.
- VET RECOMMENDED – Our no-sting pet ear cleaner has been tested and reviewed by a veterinarian to help maintain otic hygiene. Safe for pets 12 weeks and older.
- TROPICLEAN – For a tropical experience, pair this with our ear cleaning wipes and medicated itch relief pet shampoo.
10. Mender Ear Cleanser for Dogs and Cats
Mender offers an all-in-one ear cleanser that is suitable for both dogs and cats. This product helps to remove wax and debris while also soothing any irritation caused by infections. With a gentle formulation, it aims to maintain healthy ear canals in your pets.
Mender’s easy-to-use dropper makes application straightforward, ensuring that you can effectively treat your pet’s ears with minimal hassle.
Best for: Multi-pet households.
Pros:
- Suitable for both dogs and cats.
- Gentle and soothing.
- Easy to apply.
Cons:
- May not be suitable for extreme cases of infection.
- Requires regular usage for best results.
- General purpose ear cleanser
- Suited for non-infected ears
- For cleaning, drying, and removal of debris.
In 2025, these products stand out as some of the best over the counter ear infection medicine for dogs. Choosing the right one depends on your dog’s specific needs, current conditions, and preference. Always consult your veterinarian before starting any treatment to ensure the health and well-being of your beloved pet.
Buying Guide for Over-the-Counter Ear Infection Medicine for Dogs
When it comes to the health and well-being of your furry friend, prompt attention to ear infections is vital. While consulting your veterinarian is always the best option, there are various over-the-counter (OTC) treatments available for dogs. This guide will help you choose the right OTC ear infection medicine for your dog.
Understanding Ear Infections in Dogs
Common Symptoms:
- Excessive scratching or pawing at the ears
- Head shaking or tilting
- Foul odor from the ears
- Red or inflamed ear canal
- Discharge (brown, yellow, or bloody)
- Pain or sensitivity around the ears
Types of Ear Infections:
- Bacterial: Often requires antibiotics.
- Fungal: Commonly caused by yeast.
- Allergic: Can be triggered by environmental factors or food.
Key Considerations Before Buying
1. Consultation with Veterinarian:
- Always consult your vet before starting any OTC medication, especially if your dog has a pre-existing condition or is on other medications.
2. Type of Infection:
- Identify the type of infection (bacterial, fungal, or allergic) before selecting a treatment, as specific medications target different causes.
3. Ingredients:
- Look for medications that contain effective antifungal or antibacterial properties, such as:
- Clotrimazole: For fungal infections.
- Hydrocortisone: For reducing inflammation and itching.
- Benzoyl Peroxide: For combating bacteria.
4. Administration Method:
- Consider how easy the medicine is to administer. Products come in various forms:
- Drops: Ideal for localized treatment.
- Sprays: Good for larger areas and easier application.
- Wipes: Convenient and easy to use for regular cleaning.
5. Brand Reputation:
- Choose reputable brands that specialize in pet health products. Reading reviews and feedback from other dog owners can provide insight into effectiveness.
6. Packaging Size:
- Assess the size of the packaging in relation to your dog’s needs. If it’s a minor case, a smaller package may suffice, whereas more severe cases may require larger quantities.
Top Over-the-Counter Ear Infection Medicines
1. Zymox Otic Enzyme Solution
- Use: Contains enzymes that help fight bacterial, fungal, and yeast infections.
- Pros: No need for prior cleaning; safe for dogs of all ages.
- Cons: May require regular use for prevention.
2. Vet’s Best Ear Relief Wash
- Use: Combines natural ingredients like Aloe and Neem oil for relief and cleansing.
- Pros: Gentle formula suitable for sensitive ears.
- Cons: May not be effective for severe infections.
3. Pet MD Dog Ear Cleaner
- Use: Antimicrobial and antifungal solution.
- Pros: Helps in daily ear cleaning and maintenance; safe to use after swimming or bathing.
- Cons: Pre-existing infections may require additional treatment.
4. VetIQ Ear Cleaner
- Use: Helps reduce ear wax buildup and prevent infections.
- Pros: Easy to administer; made with natural ingredients.
- Cons: More of a preventative measure than a treatment.
5. MediVet Ear Cleaner
- Use: Drops that clean and soothe inflamed ear canals.
- Pros: Great for routine maintenance.
- Cons: Not a substitute for prescribed antibiotic treatment.
Usage Tips
- Follow Instructions: Always adhere to the dosage and frequency recommended on the product label.
- Observe: Keep a close eye on your dog’s symptoms. If they worsen or do not improve within a few days, consult your veterinarian immediately.
- Clean Ears: Regularly clean your dog’s ears with an appropriate cleaner to help prevent future infections.
Conclusion
Choosing the right over-the-counter ear infection medicine for your dog can greatly alleviate their discomfort and help restore their health. Prioritize consultation with your veterinarian, assess the specific needs of your dog, and select a product that has proven effective for other pet owners. Regular maintenance and monitoring can help keep your dog’s ears healthy and infection-free.
