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10 Best Lactose Free Infant Formula Picks for 2025: Top Reviews & Guide
Lactose-free infant formula is increasingly becoming the go-to choice for parents concerned about their baby’s dairy intolerance or those looking for alternative nutrition solutions for their infants. In the quest for the best lactose-free infant formula, parents must navigate various offerings to ensure they select a formula that meets their child’s nutritional needs and preferences. In 2025, Amazon remains a leading platform for purchasing these products, providing a range of suitable options. This article will review the top 10 lactose-free infant formulas available on Amazon, offering insights into their features, pros, and cons.
Top 10 Lactose-Free Infant Formulas on Amazon
1. Similac Pro-Advance Lactose-Free Infant Formula
Similac Pro-Advance Lactose-Free Infant Formula is designed with a blend of nutrients to support infants’ overall growth and development. This formula features HMO prebiotics, which are essential in promoting a healthy immune system and digestion.
The formula is free from palm olein oil, making it an excellent choice for easier digestion and better calcium absorption. With a carefully balanced ratio of proteins, carbohydrates, and fats, this formula works well for infants with lactose sensitivity.
Pros: Nutrient-rich, contains prebiotics, palm olein oil-free.
Cons: May not be suitable for all infants with dairy sensitivity due to casein content.
2. Enfamil Nutramigen with Enflora LGG Powder
Enfamil Nutramigen is a hypoallergenic formula specially designed for infants who are allergic to cow’s milk protein. This lactose-free formula not only helps manage colic due to protein sensitivity but also promotes a healthy gut microbiome with its unique blend of probiotics.
In 2025, this formula remains one of the top choices for parents looking to avoid lactose while ensuring their babies receive essential nutrients. It offers a balanced fatty acid profile that supports brain development, complemented by DHA and ARA.
Pros: Hypoallergenic, contains probiotics, promotes gut health.
Cons: It can be more expensive than standard formulas.
−$5.51
- Fast relief NOW - Manage colic due to cow’s milk allergy as early as the first feeding, with 90% of infants improving within 48 hours
- Fewer allergies LATER - Specially formulated to reduce the incidence of future allergy challenges by 50%
- Helps support baby's immune system to return to consuming traditional milk protein formula without an allergic response
- Includes the probiotic branded LGG—the most extensively studied probiotic for allergy management & supporting the digestive health of your baby
- Complete lactose-free and sucrose-free nutrition for the first 12 months. From Enfamil, the #1 Infant Formula brand recommended by pediatricians*
3. Gerber Good Start Soy Infant Formula
Gerber Good Start Soy Infant Formula offers a lactose-free alternative that is packed with several key nutrients, making it a well-rounded option for your baby. This formula is designed for infants who are lactose intolerant or have difficulty digesting cow’s milk protein.
The soy-based formula is fortified with DHA, which supports brain development, along with prebiotics that optimize digestion and intestinal health, making it suitable for sensitive tummies.
Pros: Soy-based, fortified with DHA, promotes digestive health.
Cons: Some infants may be allergic to soy; limited flavor options.
−$3.00
- Complete nutrition uniquely formulated for sensitive tummies: Created to address common feeding issues, including gas, fussiness, and spit-up.
- High quality 100% whey protein: Free from curdling that can be caused by casein protein.
- Advanced hydrolysis: An advanced 2-step hydrolysis process makes the proteins 10x smaller than intact cow's milk proteins and easy to digest.
- With Probiotic L. Reuteri: Soothe Pro helps reduce fussiness with the first bottle, as reported in study results among parents of fussy infants.
- Growth And Development: Good Start Dr. Brown's Gentle Pro and Soothe Pro powder infant formulas are the only baby formulas with a blend of DHA, HMOs & probiotics, important components like those found in breastmilk. For infants aged 0-12 months.
4. Similac Sensitive Infant Formula
Similac Sensitive is an excellent choice if you’re looking for a lactose-free infant formula designed for sensitive stomachs. This formula contains easy-to-digest proteins and carbohydrates, which help reduce fussiness and gas, two common issues with regular infant formulas.
With its blend of DHA, lutein, and Vitamin E, Similac Sensitive not only supports brain building but also helps in the development of your baby’s eyes.
Pros: Easy to digest, helps reduce fussiness, supports brain and eye development.
Cons: Contains corn syrup as a sweetener.
- GET MORE REWARDS POINTS: Scan the MySimilac QR code on select products to earn points toward a Reward
- DESIGNED FOR BABY’S FUSSINESS & GAS: Our sensitive formula for babies is specially designed for fussiness and gas due to lactose sensitivity
- SUPPORTS BRAIN & EYES: Has DHA and lutein, important ingredients found in breast milk
- NO PALM OLEIN OIL: Designed to support excellent calcium absorption
- NO ARTIFICIAL GROWTH HORMONES: Similac was the first leading infant formula brand with no artificial growth hormones
5. Baby’s Only Organic Soy Milk Formula
Baby’s Only Organic Soy Milk Formula is a great choice for parents seeking organic products. This lactose-free formula is designed for toddlers as well and is based on organic soy protein. It’s a complete nutritional formula supported by essential vitamins and minerals.
Notably, Baby’s Only does not contain any added sugars, artificial colors, or preservatives, making it a clean option for parents concerned with additives.
Pros: Organic ingredients, no added sugars, versatile for toddlers.
Cons: Limited availability, high price point compared to non-organic options.
- ORGANIC, LACTOSE SENSITIVE FORMULA: Our Organic Sensitive Toddler Drink (formerly known as LactoRelief) is developed for toddlers with lactose sensitivities. The toddler drink powder features American dairy as its primary protein source, making it a great no-soy alternative.
- CERTIFIED ORGANIC AND CLEAN: Baby's Only Organic Sensitive toddler drink provides a safe and clean option for your toddler. Proudly bearing the USDA Organic Seal and Clean Label Purity Award, this organic toddler drink meets stringent safety standards.
- CONTAINS 25 ESSENTIAL NUTRIENTS: Our organic toddler drink is packed with only the good stuff. Fortified with organic DHA and ARA, each serving of our toddler drink contains protein, iron, vitamin D, zinc, vitamin A, calcium, and more essential nutrients.
- EASY TO PREPARE: For every two (2) fluid ounces of water, add one (1) unpacked level scoop of our powdered milk. Secure the cap on the cup and shake well until the toddler milk powder is dissolved.
- COMMITTED TO SAFETY: Your little one means the world to you, and that means the world to us. That's why our products are meticulously crafted in small batches at our state-of-the-art facility in Ohio and rigorously examined to ensure we never compromise on purity, safety, and quality.
6. Earth’s Best Organic Dairy Free Infant Formula
Earth’s Best Organic Dairy Free Infant Formula is tailored for infants with lactose intolerance, featuring a unique blend of organic ingredients. This formula is made with brown rice syrup and is fortified with DHA and ARA to aid cognitive development and supports a healthy digestive system with probiotics.
With no artificial flavors or preservatives, parents can rest assured that they are feeding their babies a nutritious alternative that is clean and wholesome.
Pros: Organic, no artificial ingredients, supports immune and digestive health.
Cons: Some parents report difficulty mixing; may be expensive.
−$12.00
- Nutrition First: Made with organic* milk from grass and grain-fed cows (!), our Dairy Infant Formula with Iron has lutein, prebiotics, and DHA and ARA to give your baby nutrients that support the body’s defenses, brain, and eye development
- Like Breast Milk: This formula is our closest to breast milk and contains no added corn syrup. This easy-to-digest (1) formula meets FDA requirements for infant nutrition****
- Made for Ages and Stages: Dairy Infant Formula is great for supplementing breastfeeding or as a replacement to nourish your baby for the first year until they are ready to transition to whole milk or a milk alternative
- Easy Prep: The container has simple instructions explaining the water-to-formula ratio, which allows you to prepare your baby’s bottle in a few simple steps. When properly diluted, this container will make approximately 155 fl. oz. of formula
- Good Food Made Fun: Earth’s Best Organic has a complete collection of organic* baby food, formula, and toddler snacks. Choose from baby food for ages 4 to 24 months, puree pouches, gentle baby formula, baby cereal, pus, finger foods, and much more
7. Happy Baby Organic Company Superfood Puffs
Though not a traditional formula, Happy Baby Organic Company offers a unique snack for lactose-intolerant infants that enrich their diets between feedings. These puffs are made with organic ingredients and provide a crunchy texture that babies enjoy while introducing a range of flavors.
It’s a versatile option for parents looking to diversify their baby’s palate while adhering to lactose-free diets. Each serving is made with real fruits and vegetables and is fortified with important vitamins and minerals.
Pros: Organic, diverse flavors, easy to digest.
Cons: Intended as a snack, not a complete nutrition source; some babies may not like the texture.
- The Perfect 1st Snack for Baby’s developing gums, our easily dissolving, organic teething wafers soothe and delight They’re made with jasmine rice flour, a touch of organic fruits and vegetables, and contain no artificial flavors for truly happy smiles
- Stage One Eaters: Happy Baby's line of Stage 1 baby foods are designed for your baby's sensitive palate Made from organic fruits & vegetables, these baby food pouches are a great way to introduce your baby to solid foods & delicious, organic ingredients
- Happy Baby: At Happy Baby Organics, we provide organic and delicious options for your baby's nutritional journey We develop premium organic recipes perfectly matched with your child's age and stage This is enlightened nutrition for every family
- Mindfully Made: We develop premium organic recipes perfectly matched with your child's age and stage Explore our snacks & meals for growing babies, toddlers & kids, from baby food pouches to freeze-dried yogurt treats, organic Cereals & Toddler Snacks
- Happy Baby:For happy tummies and Happy Tots, try Happy Baby's full line of baby food pouches, organic Cereals, teething wafers & baby snacks and more
8. Nutrilon Lactose-Free Formula
Nutrilon Lactose-Free Formula is an effective solution for infants requiring a lactose-free diet. Designed in European nutrition standards, Nutrilon incorporates a blend of essential nutrients required for healthy growth and development. It includes a mix of probiotics vital for gut health, promoting a robust immune system.
The formula is easy for babies to digest while providing critical fatty acids for neural growth, making this option well-balanced for sensitive infants.
Pros: Rich in vitamins, contains probiotics, easy to digest.
Cons: May not be readily available in the U.S.; higher price point.
−$5.51
- Fast relief NOW - Manage colic due to cow’s milk allergy as early as the first feeding, with 90% of infants improving within 48 hours
- Fewer allergies LATER - Specially formulated to reduce the incidence of future allergy challenges by 50%
- Helps support baby's immune system to return to consuming traditional milk protein formula without an allergic response
- Includes the probiotic branded LGG—the most extensively studied probiotic for allergy management & supporting the digestive health of your baby
- Complete lactose-free and sucrose-free nutrition for the first 12 months. From Enfamil, the #1 Infant Formula brand recommended by pediatricians*
9. Aptamil Lactose-Free Infant Formula
Aptamil Lactose-Free Infant Formula is another stellar choice for lactose-intolerant children. This formula is designed with advanced nutritional research and contains essential vitamins and minerals that promote growth. Aptamil includes prebiotics, improving gut health without the burden of lactose.
This option is popular among parents globally and is known for its gentle formulation, making it a favorite among sensitive infants.
Pros: Gentle formulation, supports gut health, well-balanced nutrition.
Cons: Availability may vary in the U.S.; may come with higher shipping fees.
- APTAMIL CARE STAGE 2 BABY FORMULA: Complete Nutrition for Baby, Aptamil Care 2 baby formula is specifically designed for babies born by C section also features key vitamins & minerals found in breast milk. Suitable for babies from 6+ months
- DESIGNED FOR BABIES BORN BY C-SECTION: Aptamil Care provides a unique blend of dual prebiotics GOS/FOS and probiotic B. breve M-16V to help rebalance the gut microbiome of c-section born babies to be closer to that of vaginally born babies, to help support the developing immune system. Bifidobacteria breve (B. breve) is a naturally occurring culture found in the gut of healthy, breastfed infants. This formula is made with Aptamil’s patented probiotic B. breve M-16V
- SUPPORTS BRAIN, EYE DEVELOPMENT & IMMUNE SUPPORT: Aptamil Care 2 delivers expert-recommended DHA for brain and eye development and made with our patented strain of probiotic B. breve M-16V with dual prebiotics GOS/FOS & 2’FL HMO (human milk oligosaccharide) to help support baby’s immune system
- #1 FORMULA BRAND IN EUROPE: FDA permitted and now available for purchase in the US, formula that has been inspired by 50 years of advanced breastmilk research. *Source Euromonitor International Limited; Among the brands of Follow-on Milk Formula. Based on data reported by Euromonitor International Limited, Packaged Food 2022 edition, value sales RSP, 2021 data. Aptamil includes Almiron, Aptamil, Bebilon, Gallia and Nutrilon
- APTAMIL’s QUALITY ASSURANCE: Aptamil is committed to producing quality formula. At every stage of their development, Aptamil formulations are crafted with the care and expertise that every parent and baby deserves, undergoing a comprehensive and complete series of checks to give families confidence in choosing Aptamil
10. Holle Organic Pre Formula
Holle Organic Pre Formula is a premium lactose-free option ideal for infants with feeding issues. This organic formula is designed for babies from birth to six months and is made with high-quality ingredients without any GMOs or additives. Holle is well-regarded for its rigorous quality control and dedication to providing safe infant nutrition.
The formula is rich in essential fats and proteins that contribute to healthy growth and brain development, adhering to European organic standards.
Pros: High-quality ingredients, free from GMOs, promotes healthy growth.
Cons: Premium pricing; limited availability outside of Europe.
- European Organic Quality Parents Trust Made in Germany using high-quality skimmed cow milk with Clean Label Project purity certification.
- Supports Growth & Brain Development Contains DHA (Omega-3), Iron, and Vitamins A, D & E for nutritional support during early years.
- Gentle on Little Tummies Formulated with partly demineralized whey powder for easy digestion and nutrient absorption.
- No Artificial Ingredients Free from corn syrup, artificial flavors, colors, or preservatives to ensure a clean and natural choice.
- Convenient & Versatile Feeding Option Shelf-stable for 18 months and mixes easily into bottles or foods for daily feeding routines.
Buying Guide: Lactose-Free Infant Formula
When selecting a lactose-free infant formula for your baby, it’s crucial to understand your options, features, and what factors to consider. This guide will help you make an informed choice.
1. Understand the Basics
What is Lactose-Free Formula?
Lactose-free infant formula is designed for babies who have lactose intolerance or difficulty digesting lactose. It provides the necessary nutrients without the lactose found in standard formulas.
2. Types of Lactose-Free Formulas
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Cow’s Milk-Based Formulas: These are the most common types and are modified to remove lactose. They contain proteins and fats from cow’s milk.
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Soy-Based Formulas: Made from soy protein, these formulas are suitable for babies with lactose intolerance or those who follow a vegetarian diet.
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Hydrolyzed Formulas: These formulas contain proteins that are broken down into smaller pieces to make them easier to digest. They’re often recommended for babies with allergies or a higher sensitivity to proteins.
3. Nutritional Content
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DHA and ARA: These are fatty acids important for brain and eye development. Look for formulas that include these nutrients.
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Iron Content: Ensure that the formula contains adequate iron, which is crucial for your baby’s growth and development.
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Vitamins and Minerals: Check for formulas fortified with essential vitamins and minerals, such as vitamin D and calcium.
4. Ingredients to Note
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Avoid Added Sugars: Look for formulas with minimal added sugars to promote healthy growth.
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Check for Allergens: If your child has known allergies, confirm that the formula does not contain any allergens like soy or specific proteins.
5. Brand Reputation and Reviews
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Reputable Brands: Choose formulas from established brands known for quality and safety.
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Read Reviews: Look for feedback from other parents to assess how well the formula worked for their infants.
6. Budget Considerations
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Cost: Lactose-free formulas can be more expensive than regular formulas. Compare prices and look for sales or bulk purchase options.
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Health Insurance: Check if your health insurance covers infant formulas, especially if your baby requires specialty formulas.
7. Consult Your Pediatrician
Before making a decision, consult with your pediatrician. They can provide guidance based on your baby’s individual health needs and help you choose the best formula.
8. Transitioning Tips
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Gradually Introduce: If switching from a regular formula to a lactose-free option, do so gradually to allow your baby’s digestive system to adjust.
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Observe Reactions: Monitor your baby for any adverse reactions as they adjust to the new formula, such as changes in stool, gas, or fussiness.
9. Storage and Shelf Life
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Check Expiry Dates: Always check the expiration date before purchasing.
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Storage Instructions: Follow storage guidelines carefully to preserve the formula’s quality and safety.
10. Sample Sizes
If possible, start with smaller sample sizes to determine if your baby tolerates the formula well before committing to a larger purchase.
Conclusion
Choosing the right lactose-free infant formula involves careful consideration of your baby’s unique needs, nutritional requirements, and your preferences. With a thoughtful approach, you can find the ideal formula that supports your baby’s health and growth.
