10 Best USB to MIDI Interfaces for Musicians in 2025

In the world of music production, having the right equipment can significantly enhance your creative process and workflow. One essential piece of equipment is a USB to MIDI interface, especially for those working with digital audio workstations (DAWs) and MIDI instruments. If you’re on the hunt for the best USB to MIDI options available, you’ve come to the right place. After extensive research on Amazon, we have compiled a list of the top 10 USB to MIDI interfaces that stand out in 2025.

1. MIDIBOX USB MIDI Interface

The MIDIBOX USB MIDI Interface has gained popularity for its robust build and versatile functionality. This interface supports up to 16 channels of MIDI input and output, making it an excellent option for both live performances and studio sessions. Its compact size facilitates easy portability, ensuring you can take it anywhere you go.

**Best for:** Musicians on the go, especially performers who require a reliable and compact solution for MIDI connectivity.

**Product Review:** The MIDIBOX offers a sleek design with high-quality connectors. It provides latency-free transmission, ensuring that your MIDI signals are sent in real-time without lag. Compatible with all major DAWs, the interface also requires no additional drivers, allowing for a plug-and-play experience. It’s powered by USB, adding to its convenience.

**Pros:**

  • Compact and lightweight design
  • Supports 16 channels of MIDI in/out
  • No additional drivers needed
  • Real-time latency-free transmission

**Cons:**

  • Limited feature set compared to more advanced interfaces
  • Some users report durability issues over time

  • [Premium] Developed by CME with 30+ years of experience and contributing board member of the MIDI Association, providing trusted, human-centric 24/7 support via cme-pro(dot)com/support, lifetime updates, and hassle-free replacement.
  • [Computers] Explore 2025 tech with advanced MIDI features: filter, mapping, routing. USB MIDI cable (1-in-1-out), 16 channels. Plug & play on macOS, iOS, Windows, Android, Linux, ChromeOS—no drivers needed!
  • [Instruments] Handy colored MIDI plugs. Smart LED indicators. Works with all MIDI instruments including digital drum, digital piano, portable keyboard, MIDI controller, synthesizer, EWI and groovebox.
  • [Performance] Ultra-fast 32-bit processor for extreme accuracy, high-speed optocoupler for error-free transmission, close to zero latency and jitter. High quality 6.5ft (2m) cable with all technology integrated into USB connector to reduce cable clutter
  • [MIDI] Supports all MIDI channels and messages, including notes, controllers, clock, sysex, MTC & MPE. Free UxMIDI Tools software (Mac/Win) for MIDI filtering (per channel) and MIDI routing (merge/split).

2. Roland UM-ONE mk2 MIDI Interface

The Roland UM-ONE mk2 MIDI Interface is well-regarded for its reliability and excellent performance. Featuring a 1-in/1-out MIDI configuration, this interface is user-friendly and designed to connect your MIDI keyboard or controller seamlessly to your computer.

**Best for:** Beginners or casual musicians looking for a hassle-free way to connect their MIDI gear.

**Product Review:** With a 1ms latency, the Roland UM-ONE mk2 ensures your MIDI performance is not only swift but also precise. It comes with a USB power supply, and its built-in MIDI LED indicators provide feedback, making it easy to confirm data transmission at a glance. Its compact design means it fits easily into your studio setup or gig bag.

**Pros:**

  • Excellent latency performance
  • LED indicators for easy monitoring
  • Compact and portable
  • User-friendly plug-and-play setup

**Cons:**

  • Limited to a single MIDI input/output
  • Not ideal for more complex setups

−$5.00
  • One-in/one-out MIDI interface with high-performance FPT processing
  • Compatible with Mac and Windows operating systems, and now with iOS on the iPad via the Apple iPad Camera Connection Kit
  • Data indicators for both MIDI input and output
  • Conveniently integrated USB and MIDI cables
  • USB bus-powered operation

3. Yamaha UX16 USB MIDI Interface

The Yamaha UX16 USB MIDI Interface is another solid choice for musicians looking for reliable MIDI connectivity. Boasting a straightforward design, it features 16 MIDI channels and cables to facilitate connections with just about any MIDI device.

**Best for:** Users looking for a trusted brand that specializes in music equipment.

**Product Review:** The Yamaha UX16 supports all major operating systems, which means you can easily connect it to Windows or Mac devices. Its elegant design emphasizes durability, along with MIDI IN and OUT LEDs that provide visual feedback. The interface is powered via USB, which enhances its portability.

**Pros:**

  • Compatible with multiple operating systems
  • Robust construction
  • MIDI LED indicators for visual performance checking
  • Supports a comprehensive range of MIDI gear

**Cons:**

  • Not as compact as some newer models
  • May require advanced knowledge for intricate setups

4. IK Multimedia iRig MIDI 2

For musicians who need to connect their MIDI gear to iOS devices and computers, the IK Multimedia iRig MIDI 2 is a fantastic solution. It’s especially suited for mobile musicians who rely on apps for their music production.

**Best for:** Those who use mobile devices significantly in their music production workflow.

**Product Review:** The iRig MIDI 2 boasts a user-friendly design, featuring a 5-pin MIDI IN/OUT configuration and a special connector for iOS, Android, and USB devices. It includes MIDI LED indicators to help monitor data traffic. The lightweight construction makes it highly portable, perfect for on-the-go music creation.

**Pros:**

  • Designed for mobile musicians
  • Compatible with various devices (iOS, Android, USB)
  • MIDI LED indicators
  • Highly portable and lightweight

**Cons:**

  • May require adapters for some devices
  • Limited features compared to more professional MIDI interfaces

  • Universal MIDI interface for iOS, Mac and PC; Ultra
  • portable, pocket
  • sized form factor

5. M-Audio USB MIDISPORT 2×2 Anniversary Edition

The M-Audio MIDISPORT 2×2 is perfect for musicians requiring multiple MIDI connections. This anniversary edition provides reliable performance with its enhanced features and updated design.

**Best for:** Professional musicians and producers needing multiple simultaneous MIDI connections.

**Product Review:** Offering 2 MIDI inputs and 2 MIDI outputs, this interface makes it easy to connect multiple MIDI devices at once. The MIDI throughput is also excellent, boasting minimal latency. The software bundle included is a valuable addition for those looking to dive directly into music production.

**Pros:**

  • Supports multiple MIDI devices
  • Low latency transmission
  • Includes software bundle
  • Durable design suitable for studio use

**Cons:**

  • Bulky design not ideal for singers on the move
  • Can be more expensive than basic options

  • Perfect for connecting a keyboard or controller to your computer
  • Installation is external, so no need to open the computer case
  • Powered by USB port, so no searching for a free power outlet
  • Upward Mobility - add as many USB Midisport interfaces to your computer as you have USB ports
  • Built-in USB cable and MIDI extension cables

6. ESI MIDI Mate USB MIDI Interface

The ESI MIDI Mate is a highly rated USB MIDI interface known for its exceptional performance and features at an affordable price point. It is perfect for beginners and professionals alike.

**Best for:** Users needing a budget-friendly option without sacrificing quality.

**Product Review:** It offers 16 MIDI inputs and outputs and is compatible with most DAWs. With its intuitive design, MIDI Mate features LED indicators for both channels, ensuring that you are always aware of your connections. The compact size and plug-and-play functionality make it a hassle-free solution.

**Pros:**

  • Affordable without compromising on quality
  • Multiple MIDI IN/OUT channels
  • LED indicators for channel status
  • Compatibility with all major DAWs

**Cons:**

  • Limited to USB-powered devices
  • Basic features compared to higher-end models

−$6.00
  • EXTENDED REACH: Experience unparalleled flexibility with the MIDIMATE eX MIDI to USB cable, stretching a generous 2 meters (6.5 feet). Equipped with dual MIDI connectors, it supports an expansive range of up to 32 inputs or outputs, making it perfect for extensive MIDI setups
  • HIGH-SPEED COMPATIBILITY: The MIDIMATE eX ensures ultra-fast, seamless MIDI to USB connections, optimized for USB 3.0 and 2.0. Fully backward compatible with USB 1.1, it guarantees smooth integration with both PC and Mac for a flawless user experience
  • SUPERIOR BUILD QUALITY: Rely on the robust MIDIMATE eX MIDI Interface, designed to endure the rigors of daily studio use and live performance with its durable construction and reliable performance
  • PLUG & PLAY CONVENIENCE: Connect instantly with the USB to MIDI cable, effortlessly interfacing with PCs or Macs without the need for drivers. Jumpstart your music creation with immediate, hassle-free connection to MIDI devices
  • WINDOWS ENHANCED: The MIDIMATE eX USB MIDI cable comes with an optional ESI MIDI Port driver, enabling sophisticated multi-device and multi-client operations to amplify your studio's potential

7. Korg microKEY Air 37 MIDI Controller

The Korg microKEY Air 37 is more than just a MIDI interface; it’s a portable MIDI controller that connects wirelessly to your devices. This makes it a great option for performers and creators who are always on the move.

**Best for:** Musicians who prefer wireless functionality and portability in their MIDI solutions.

**Product Review:** This MIDI controller features 37 velocity-sensitive keys and Bluetooth connectivity, making it incredibly versatile. It can also be used in wired mode. The microKEY Air includes a software bundle that gives you access to music production apps and virtual instruments.

**Pros:**

  • Wireless and wired connectivity options
  • Velocity-sensitive keys for dynamic performance
  • Compact and lightweight
  • Comes with a comprehensive software bundle

**Cons:**

  • Battery-powered, may require frequent charging
  • Limited control options compared to full-sized controllers

  • Bus-powered 37-key USB/Bluetooth Keyboard Controller with Mod Wheel
  • Damper Pedal Input
  • Class-compliant
  • Pitch Wheel

8. Alesis Core 1 USB Audio Interface

While technically an audio interface, the Alesis Core 1 includes a MIDI interface feature that makes it one of the most versatile options available. This dual functionality allows musicians to record both audio and MIDI, all within one device.

**Best for:** Musicians who need both audio and MIDI capabilities in a single interface.

**Product Review:** The Alesis Core 1 features a low-impedance instrument input and MIDI IN/OUT for seamless connectivity. With 24-bit/96 kHz audio resolution, you can expect high-quality sound. The core 1 is designed for those looking to produce live performances and studio recordings with ease.

**Pros:**

  • Dual audio and MIDI capabilities
  • High audio resolution for quality recordings
  • Compact and portable design
  • Easy-to-use interface

**Cons:**

  • Less specialized for MIDI than dedicated interfaces
  • Can be more expensive due to dual functionality

  • Pro performance with great pre-amps - Achieve a brighter recording thanks to the high performing mic pre-amps of the Scarlett 3rd Gen. A switchable Air mode will add extra clarity to your acoustic instruments when recording with your Solo 3rd Gen
  • Get the perfect guitar and vocal take with - With two high-headroom instrument inputs to plug in your guitar or bass so that they shine through. Capture your voice and instruments without any unwanted clipping or distortion thanks to our Gain Halos
  • Studio quality recording for your music & podcasts - Achieve pro sounding recordings with Scarlett 3rd Gen’s high-performance converters enabling you to record and mix at up to 24-bit/192kHz. Your recordings will retain all of their sonic qualities
  • Low-noise for crystal clear listening - 2 low-noise balanced outputs provide clean audio playback with 3rd Gen. Hear all the nuances of your tracks or music from Spotify, Apple & Amazon Music. Plug-in headphones for private listening in high-fidelity
  • Everything in the box: Includes Pro Tools Intro+, Ableton Live Lite, six months of FL Studio Producer Edition and Hitmaker Expansion: a suite of effects, software instruments, and easy-to-use mastering tools

9. FastTrack USB MIDI Interface

The FastTrack USB MIDI Interface is an excellent addition to any musician’s setup. It’s particularly suitable for those who want simple yet reliable functionality.

**Best for:** Amateur musicians who want a straightforward but effective MIDI connection.

**Product Review:** This interface includes MIDI IN and OUT ports along with a USB connector that requires no external power source, making it incredibly straightforward to use. With solid build quality and a performance-oriented design, the FastTrack is perfect for musicians who need to focus on their creativity without dealing with complex setups.

**Pros:**

  • Simplistic design makes it easy to use
  • No external power required
  • Reliable performance, particularly for beginners

**Cons:**

  • Limited features compared to high-end models
  • Cable length may be restrictive in some setups

  • 9V AC/DC Adapter Power Supply Charger Cord for M-Audio Fast Track Pro
  • Input Voltage : AC 100-240V Output Voltage : DC 9V Input Frequency : 50-60Hz
  • Industry Quality : Over Voltage Protection, Over Heat Protection, CE
  • Package include: 1 x Adapter Charger
  • Compatible with: M-Audio Fast Track Pro

10. Focusrite Scarlett 2i2 (3rd Gen)

Like the Alesis Core 1, the Focusrite Scarlett 2i2 is primarily an audio interface that includes MIDI functionality. It is among the most popular audio interfaces, often recommended for both studio and home use.

**Best for:** Musicians who focus heavily on audio production but still require MIDI connectivity.

**Product Review:** The Scarlett 2i2 features 2 microphone preamps and MIDI I/O in one compact unit. This interface is powered by USB and provides high-quality audio recording, making it ideal for professional environments. The comprehensive software included gives users all they need to start creating immediately.

**Pros:**

  • High-quality audio recording
  • MIDI connectivity for added versatility
  • User-friendly interface with good latency
  • Comes with a comprehensive software package

**Cons:**

  • Primarily focused on audio, MIDI features may be secondary
  • More expensive than dedicated MIDI interfaces

−$30.00
  • The new generation of the artist's interface: Connect your mic to Scarlett's 4th Gen mic pres. Plug in your guitar. Fire up the included software. Start making your first big hit
  • Studio-quality sound: With a huge 120dB dynamic range, the newest generation of Scarlett uses the same converters as Focusrite’s flagship interfaces, found in the world's biggest studios
  • Never lose a great take: Scarlett 4th Gen's Auto Gain sets the perfect level for your mic or guitar, and Clip Safe prevents clipping, so you can focus on the music
  • Find your signature sound: Air mode lifts vocals and guitars to the front of the mix, adding musical presence and rich harmonic drive to your recordings
  • With Scarlett 4th Gen, you have all you need to record, mix and master your music: Includes industry-leading recording software and a full collection of record-making plugins

With this comprehensive guide on the best USB to MIDI interfaces available on Amazon in 2025, you should have no trouble finding the perfect option to enhance your music production workflow. Whether you are a seasoned professional or just starting, the right interface can transform your creative process and take your music to the next level.

Buying Guide: USB to MIDI Interfaces

If you’re looking to connect your MIDI devices to a computer or other digital audio workstation (DAW), a USB to MIDI interface can be essential. This guide will help you understand what to look for when choosing the right USB to MIDI device for your needs.

Key Features to Consider

1. Connection Type

  • USB Jack: Ensure the interface has a standard USB type-A or type-C connector that is compatible with your computer.
  • MIDI Ports: Look for both MIDI In/Out ports (and possibly Thru) depending on your setup requirements.

2. Compatibility

  • Operating System Support: Check if the interface is compatible with Windows, macOS, and/or Linux.
  • DAW Compatibility: Ensure it works smoothly with the software you plan to use (e.g., Ableton, FL Studio, Logic Pro).

3. Latency

  • Lower latency is crucial for real-time performance. Check for any specifications or reviews regarding latency performance.

4. Power Supply

  • Some interfaces are USB-powered, eliminating the need for an external power source, while others may require a power adapter.

5. Driver Requirements

  • Look for a device that is class-compliant, meaning it doesn’t require special drivers and can work out-of-the-box with your system.

6. Number of MIDI Channels

  • Consider how many MIDI channels you need. Some interfaces can handle multiple MIDI devices simultaneously, which is useful for more extensive setups.

7. Build Quality

  • Look for sturdy construction, especially if you’ll be using it in a live setting or travelling frequently.

8. Additional Features

  • MIDI Monitoring Indicators: LED lights that show when MIDI data is being transmitted.
  • MIDI Routing Software: Some interfaces come with bundled software that allows for routing and managing MIDI signals.

Popular Brands to Consider

  • M-Audio: Known for reliable products at an affordable price.
  • Roland: Offers premium quality and durability, often with extra features.
  • Focusrite: Recognized for their excellent audio interfaces and MIDI solutions.
  • Yamaha: Provides versatile and reliable products for various music setups.

Price Range

  • Budget Options ($20 – $50): Basic interfaces suitable for beginners.
  • Mid-Range ($50 – $150): More features, better build quality, and low latency.
  • Professional ($150 and up): High-end devices with advanced features, perfect for studio environments.

Recommendations

  • For Beginners: Consider the M-Audio MIDIsport for its affordability and ease of use.
  • For Intermediate Users: The iRig MIDI 2 provides additional features like iOS compatibility.
  • For Professionals: The Roland UM-ONE mk2 offers excellent performance and build quality.

Conclusion

Investing in a USB to MIDI interface can significantly enhance your music production workflow. Assess your needs based on the features and budget outlined in this guide to find the perfect device for your setup. Happy music making!

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William Quick
William Quick

Passionate about uncovering the best products for everyday life, I provide honest, detailed, and unbiased reviews to help you make smarter buying decisions. From tech gadgets to home essentials, I test and analyze each item thoroughly to highlight what truly matters—quality, usability, and value. Follow along for trusted insights that simplify your shopping experience and ensure you get the most out of every purchase.

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