10 Best Gainer Protein Supplements for Muscle Growth in 2025

In the quest for muscle gain, gainer protein supplements have become increasingly popular among fitness enthusiasts and athletes. These products are designed to help individuals add calories and nutrients to their diet efficiently, helping achieve their goals faster. When searching for the best gainer protein on Amazon, users often look for high-quality ingredients, taste, and value for money. In this comprehensive review, we will explore the top 10 gainer protein products available on Amazon in 2025, diving into their features, benefits, and potential drawbacks.

1. Optimum Nutrition Serious Mass

Optimum Nutrition Serious Mass is one of the most recognized names in the gainer protein category. This supplement is specifically designed for individuals trying to gain weight and build muscle mass, packed with an impressive amount of calories per serving.

Features include 1,250 calories per serving, 50 grams of protein, and a mix of various carbs to fuel workouts. It also includes 24 vitamins and minerals to bolster overall health. The product is gluten-free and available in various flavors to cater to different taste preferences.

Pros: Excellent calorie count per serving, blends well with water or milk, various flavors;
Cons: High in sugar, which may not be suitable for everyone, can be too thick for some.

−$5.02
  • HIGH CALORIE WEIGHT GAINER: More than 1,200 calories per 2-scoop serving
  • 50 grams of blended protein per 2-scoop serving
  • Over 250 grams of carbohydrates per 2-scoop serving
  • With over 20 vitamins and minerals including Vitamin C and Zinc to provide immune support
  • MORE VERSATILITY: Using an electric blender, add fresh or frozen fruits, peanut butter, nuts, and other calorie dense foods to boost your weight gain potential

2. BSN True Mass

BSN True Mass offers a balanced approach to mass gaining. With 700 calories and 46 grams of protein per serving, it’s formulated to provide the essential nutrients for recovery and muscle growth.

This product also contains healthy fats from medium-chain triglycerides (MCTs) and dietary fiber, making it an excellent choice for those looking to improve digestion. True Mass is available in a myriad of flavors, enhancing the overall experience of consumption.

Pros: Rich protein blend, contains healthy fats, good taste;
Cons: Calorie-dense, may lead to unwanted fat gain if not monitored.

−$9.05
  • TRUE-MASS: 700 CALORIES PER SERVING – the extra nutrition your body needs to build mass in an extreme training program.
  • 2:1 RATIO OF CARBS & PROTEIN – provide your body a high-quality mix of carbs and protein to support your mass gaining goals
  • 46G-50G PROTEIN FROM ULTRA-PREMIUM PROTEIN SOURCES – whey protein concentrate, calcium caseinate, milk protein isolate, whey protein isolate, micellar casein, hydrolyzed whey protein, and egg whites
  • Medium chain triglycerides (MCT) FATS – round out the nutritional value of each shake and complement BSN's legendary great taste
  • BSN FLAVOR TECHNOLOGY – Unbeatable taste and consistency for a milkshake-like experience you’ll always love, with several craveable flavor options

3. MuscleMilk Gainer Protein Powder

MuscleMilk Gainer Protein Powder is an effective choice for individuals looking to build their muscle mass without compromising on flavor. This product combines protein with essential nutrients, serving up 32 grams of protein and 1200 calories per serving.

The innovative blend of fast- and slow-release proteins allows for sustained energy levels, making it ideal for post-workout recovery. It’s also easy to mix, ensuring a smooth texture without clumping.

Pros: Good flavor profile, easy mixing, supports recovery well;
Cons: Might include artificial sweeteners, some may find it too sweet.

  • Contains one (1) 5 pound cannister (about 14 servings) of Muscle Milk Pro Series Gainer Protein Powder Supplement. Packaging may vary. Shaker bottle sold separately
  • Key Features Muscle Milk Gainer Powder Contains 32 Grams of Protein, 3 Grams of Leucine From Milk Proteins, and 650 Calories in Every 4 Scoops (162g), the Recommended Usage for Individuals Looking to Build Size and Gain Muscle Mass
  • Usage Muscle Milk Gainer Powder Can Be Used Pre Workout, Post Workout or as an Anytime Protein Rich Meal Option or Snack
  • Great Tasting Shak Mix 4 scoops (162g) MUSCLE MILK Gainer Powder into 10 16 fluid ounces water for a Great Tasting Shak; You can also add it to pancakes, smoothies or other recipes to increase the protein content
  • Work Out; Refuel; Rebuild; Advance; Consuming Both Fast and Slow Release Proteins, Like Those Found in Muscle Milk Gainer, Helps Keep Your Body in Positive Protein Balance
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4. Dymatize Super Mass Gainer

Dymatize Super Mass Gainer is designed for those who are serious about building mass with a robust formula delivering 1,300 calories and 52 grams of protein per serving. This product also features a blend of vitamins and minerals crucial for overall health.

With a good mix of carbohydrates, it aids in replenishing glycogen stores post-workout. Super Mass Gainer is well-received due to its great taste and variety of flavors.

Pros: Diverse flavors, effective for gaining mass, contains BCAAs for muscle recovery;
Cons: Might be too caloric for those who don’t require that many calories.

−$2.48
  • 52G PROTEIN: Every servings contains 52g of protein to support muscle growth, repair, and recovery. If your goal is gaining muscle size and strenth, then SMG is your perfect workout parther. while recovering from intense workouts and pushing limits in the gym
  • CALORIE-DENSE FORMULA: With 1,280 calories per serving, this weight gainer offers a substantial caloric boost for individuals aiming to gain muscle mass and meet their energy needs
  • ENHACED WITH CREATINE AND NUTRIENTS: Each serving provides 1g of creatine to support the increase in power and strength you need to maximize training. Plus 14 essential vitamins and minerals, including Vitamin C, E, and calcium, to support overall health and recovery
  • CONTINUOUS GROWTH: Dymatize Super Mass Gainer combines fast- and slow-digesting proteins, like whey and casein, to fuel muscle growth and recovery with sustained protein delivery for long-lasting results for men and women
  • YOUR WAY OF GAINING: Get creative by blending mass gainer into smoothies with fruits, peanut butter, and oats. It’s also perfect for adding to protein bars, cookies, and pancakes for delicious, calorie-packed treats

5. Universal Nutrition Real Gains

Universal Nutrition Real Gains is a balanced gainer supplement, boasting 600 calories and 52 grams of protein per serving. This product is formulated with a blend of proteins, carbs, and healthy fats, creating a well-rounded option for those looking to gain weight healthily.

It also includes fiber and essential vitamins, promoting superior digestion and overall well-being. The flavor options are versatile, appealing to a wide range of consumers.

Pros: Balanced macronutrient ratio, promotes healthy weight gain, good mixing ability;
Cons: Lower calorie count might not suit those with higher caloric needs.

  • The Anabolic Potential of Beef in Convinent Tablet Form
  • 3 Grams of pure beef protein isolate per serving
  • Triple combination beef protein isolates, beef albumin and Argentine liver
  • Contains a full spectrum of highly concentrated amino acids
  • Manufactured in a cGMP manufacturing facility in New Brunswick, New Jersey. We manufacture all of our own supplements, so we have the highest quality control from start to finish. What is on the label, is exactly what you are going to get.

6. GNC Pro Performance Bulk 1340

GNC Pro Performance Bulk 1340 is ideal for those who want a substantial calorie intake from a single source. This gainer offers a whopping 1,340 calories and 50 grams of protein per serving, perfect for bulking phases.

The blend contains a variety of carbs that help sustain energy during intense workouts. GNC also includes a complementary mix of 24 vitamins and minerals, supporting overall health and recovery.

Pros: High calorie count, rich protein content, comprehensive nutrient profile;
Cons: High in sugars, could lead to unwanted fat gain.

  • START GAINING MASS WITH A HIGH-CALORIE FORMULA: Build the size that creates big moments when you train with the blend of protein, creatine, and carbohydrates in GNC Pro Performance Bulk 1340 high-calorie mass gainer
  • SUPPORT MUSCLE ENERGY, RECOVERY, AND GROWTH WITH CREATINE & MORE: Fuel maximum results during and after intense workouts with muscle fuel from high-quality protein and 1g of creatine to support energy production
  • HIT BIGGER PROTEIN GOALS: Bulk 1340 packs 50g of whey protein powder with naturally occurring BCAA to support muscle growth—including 10g of glutamine, an amino that’s also important for supporting the immune system
  • FUEL MUSCLES WITH 1,340 CALORIES IN A MACRO BLEND: GNC Pro Performance’s most nutrient-dense blend packs enough calories and carbs to blast through your most challenging sessions in the gym
  • CHOOSE A BANNED SUBSTANCE-TESTED MASS GAINER: Unlike most mass gainers with proprietary blends, Bulk 1340 is certified Banned Substance Tested and designed to help athletes increase size and overall strength.

7. Redcon1 MRE Lite

Redcon1 MRE Lite stands out among gainer proteins as a whole-food-based option. This product provides 100% real food sources of protein, including chicken, eggs, and beef, which can be beneficial for those preferring whole food over synthetic sources.

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It contains 26 grams of protein and 270 calories per serving, focusing more on muscle recovery and maintaining gut health. The absence of artificial ingredients is a significant draw for health-conscious users.

Pros: Whole-food based, no artificial ingredients, good for digestion;
Cons: Lower calorie count, which may not meet the needs of serious bulkers.

−$14.99
  • Whole Food Protein Shake Powder - MRE Lite delivers a high protein, great taste and excellent meal replacement powder of whole foods, but with much lower carbohydrates for the person keeping a close and watchful eye on his or her macronutrients from meal supplement shakes.
  • Premium Ingredients Backed By Science - This high protein meal replacement contains keto protein and MCT oil. Commonly extracted from coconut oil, MCT (medium chain triglyceride) oil is a source of fats that the body can efficiently use as a source of energy for this low carb protein powder.
  • Professional Grade Formula - REDCON1's MRE Lite whole food high protein shakes contain a whole food protein blend of beef, salmon, chicken, egg, brown rice and pea protein powders. Each meal replacement shake is just 130 calories with 24g of protein and just 2g of sugar in this motivational protein shake.
  • Delicious Flavor Variety - We made sure every flavor is delicious, fulfilling and refreshing so as you hustle hard each day, you never have to sacrifice taste for brain focus or high performance in a protein shake again. A protein powder meal replacement should be something to look forward to as you work on your wellness journey.
  • Premium Formulated Products - REDCON1 creates only premium formulated protein replacement with transparent supplement labels that are backed by science, and packed with low carb and keto friendly ingredients such as MCT oils, 24g protein, and whey-free for easier digestion.

8. EAS 100% Whey Protein Powder

EAS 100% Whey Protein Powder, although primarily a protein supplement, can double as a gainer when mixed with other calorie-dense ingredients. Each serving provides 26 grams of protein, making it suitable for muscle recovery.

This gainer is low in calories compared to others on this list, making it a good option for lean muscle gain and when combined with oatmeal or other carbs to reach higher caloric goals.

Pros: Great taste, versatile for different recipes, low sugar;
Cons: Lower in calories, not a complete gainer on its own.

  • Hydrovon with Embedded Enzyme Technology or EET allows for maximum anabolic response. Better recovery, better absorption, and improved results by releasing Leucine and other important aminos early in the muscle synthesis process.
  • Super low calories – 25g of protein, 2g of carbs and 2g of fat in each scoop. Available in 2lb. and 5lb. tubs and in 5 craving crushing flavors.
  • Improve workout recovery, muscle mass and strength and defeat the negative catabolic effects from other inferior proteins.
  • EAS has a direct procurement of raw materials to ensure control of quality and cost while adhering to strict GMP quality standards for nutritional supplements.
  • These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.

9. Naked Mass Protein Powder

Naked Mass Protein Powder offers a minimalistic approach, containing only three ingredients: whey protein concentrate, egg white protein, and organic maltodextrin. With 1,250 calories and 50 grams of protein per serving, it’s great for those looking for clean ingredients.

The product is free from artificial sweeteners, flavors, and colors, appealing to those with dietary restrictions. Its organic maltodextrin sources carbohydrates from whole foods, aiding muscle recovery without unnecessary additives.

Pros: Clean ingredients, no artificial additives, suitable for all diet types;
Cons: Taste may not be as appealing as flavored versions, slightly grainy texture.

  • ONLY THREE INGREDIENTS: Naked Whey, Naked Casein and Organic Maltodextrin (made from gluten free organic tapioca). Naked Mass contains no artificial sweeteners, flavors, or colors and is GMO Free, No rBGH or rBST, Soy Free and Gluten Free.
  • MAXIMUM NUTRITION: 50g of Protein, 252g of Carbs, 1,250 Calories, 11.5g of BCAAs (branched-chain amino acids) per serving and only 5g sugar - compare vs other weight gain supplements for bulking.
  • MULTI-PHASE CLEAN PROTEIN: Keep protein synthesis up by combining fast release grass-fed whey with slow-digesting micellar casein. Plus, get the healthy amino acids your body needs. Combine with a high-calorie diet and exercise to gain weight and transform yourself from a hard gainer to a pro gainer.
  • PREMIUM COMPLEX CARBOHYDRATES: Unlike other weight gainer supplements that use wheat-based maltodextrins, Naked Mass is a serious, true mass gainer and uses gluten free organic tapioca maltodextrin for clean source complex carbohydrates.
  • BEST WEIGHT GAINER SHAKES AND RECIPES: Our unflavored super mass gainer protein powder is versatile for making smoothies and recipes. Boost calories and give your body optimum nutrition by adding Naked Mass to homemade protein bars, shakes, and more.
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10. Ghost Weight Gainer

Ghost Weight Gainer not only provides a high-caloric option but also focuses on taste, famously known for its bold flavors and branding. Each serving contains 1,230 calories and 50 grams of protein derived from multiple sources.

This product is also highlighted for its blend of carbohydrates and added nutrients to aid in recovery and muscle growth. Ghost emphasizes transparency by detailing exactly what goes into each scoop, allowing users to feel confident in their choice.

Pros: Great flavor options, transparent ingredient list, supports muscle recovery;
Cons: Can be high in sugars, pricier than some competitors.

  • Whey More Refreshing: GHOST Clear Whey has a light, refreshing Orange Cream taste for juicy gains that deliver as much protein as the OG GHOST WHEY. Approximately 20 servings per container.
  • 25G of Protein: Every scoop contains 25G of pure, fully disclosed whey protein isolate.
  • Zero Fat. Zero Sugars.: Clear Whey’s formula is fat and sugar free with natural colors for easy sips that create epic gains, plus it’s gluten and soy free
  • Total Transparency: All GHOST products feature a transparent label that fully discloses the dose of each active ingredient. Zero proprietary blends means you know what you’re getting in each and every scoop.
  • Be Seen: As a premium active lifestyle brand, GHOST is powering and empowering users to Be Seen beyond the walls of the gym. The name GHOST and mantra “Be Seen” come from that feeling of being behind the scenes and wanting to be heard, waiting to make an impact. We’re all Ghosts. This is our time.

Gainer Protein Buying Guide

Gainer protein supplements are popular among athletes, bodybuilders, and anyone looking to increase muscle mass and gain weight. These products typically combine protein, carbohydrates, and fats to provide a calorie-dense option for those struggling to meet their nutritional goals. Here’s a comprehensive buying guide to help you choose the best gainer protein for your needs.

1. Understand Your Goals

Weight Gain

  • Caloric Surplus: If you’re looking to gain weight, choose a gainer with a higher caloric content (more than 500 calories per serving).

Muscle Gain

  • Protein Content: Look for about 20-30 grams of protein per serving to support muscle repair and growth.

2. Key Ingredients

Protein Sources

  • Whey Protein: Fast-absorbing, ideal for post-workout recovery.
  • Casein Protein: Slow-digesting, great for overnight muscle recovery.
  • Egg Protein: Good option for those with dairy allergies.
  • Plant-Based Proteins: Options like pea, brown rice, and hemp are excellent for vegans or those with lactose intolerance.

Carbohydrates

  • Complex Carbs: Oats, sweet potatoes, or brown rice provide sustained energy.
  • Simple Carbs: Dextrose or maltodextrin can offer a quick energy boost post-workout.

Fats

  • Healthy Fats: Look for sources like MCT oil, flaxseed oil, or nuts to provide essential fatty acids.

3. Nutritional Profile

Protein-to-Carbohydrate Ratio

  • A balanced ratio helps in muscle recovery and energy replenishment. A common ratio is 2:1 or 3:1 (carbs to protein).

Calories

  • Assess your daily caloric needs and choose a gainer that fits within your macro goals.

4. Flavor and Mixability

Flavor Variety

  • Opt for flavors you enjoy. Many brands offer a range of flavors, from chocolate to vanilla to unique fruit blends.

Mixability

  • Read reviews to ensure the gainer mixes well in water or milk without clumping.

5. Brand Reputation

  • Research brands known for quality and transparency. Look for products that have been tested for purity and are free from harmful additives.

6. Additives and Fillers

  • Check the ingredient list for unnecessary fillers, artificial sweeteners, or preservatives. Ideally, choose a product with minimal ingredients.

7. Price vs. Quality

  • Higher price doesn’t always mean better quality. Compare prices per serving and make sure you’re getting a good value without compromising quality.

8. Dietary Restrictions

  • Always check for allergens if you have dietary restrictions (e.g., gluten-free, lactose-free, etc.).

9. Customer Reviews

  • Look for reviews and testimonials from users similar to you. This can provide insight into taste, effectiveness, and any side effects.

10. Consult Professionals

  • If unsure about your specific nutritional needs, consult with a nutritionist or dietitian to tailor your gainer protein choice to your individual goals.

Conclusion

Choosing the right gainer protein requires understanding your specific nutritional needs and fitness goals. By considering the factors outlined in this guide, you can select a product that best supports your journey to muscle gain and overall health. Always remember to combine your supplement use with a balanced diet and regular exercise for optimal results.

William Quick
William Quick

Passionate about uncovering the best products for everyday life, I provide honest, detailed, and unbiased reviews to help you make smarter buying decisions. From tech gadgets to home essentials, I test and analyze each item thoroughly to highlight what truly matters—quality, usability, and value. Follow along for trusted insights that simplify your shopping experience and ensure you get the most out of every purchase.

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