10 Best Over the Counter Ear Infection Medicine for Dogs in 2025

Finding the best over the counter ear infection medicine for dogs can be a challenge for pet owners. Ear infections in dogs are common and can lead to discomfort, pain, and further health issues if not treated promptly. In 2025, the availability of effective ear infection treatments on platforms like Amazon makes it easier for pet owners to find solutions. This article reviews the top 10 products available on Amazon, exploring their features, pros, and cons to help you make an informed decision for your furry friend.

Top 10 Over the Counter Ear Infection Medicines for Dogs

Zymox Otic Enzymatic Solution

Features: The Zymox Otic Enzymatic Solution is a popular choice among dog owners. Its unique enzyme formulation is designed to relieve inflammation and combat bacteria and yeast. The no-sting formula is safe for sensitive ears, making it suitable for dogs of all sizes. It comes in a convenient dropper bottle for easy application.

Best for: Bacterial and fungal ear infections, inflammation.

Product Review: Zymox is often recommended by veterinarians due to its effectiveness and safety profile. Pet owners praise its ability to reduce irritation and discomfort quickly. Many have reported positive results within a few days, making it a go-to product for minor ear infections.

Pros:
– Non-toxic and safe for all dog breeds.
– Easy to administer.
– Quick results reported by users.

Cons:
– May be more expensive than other options.
– Requires consistent use for best results.

  • Cat and dog ear cleaner, soothes recurrent ear issues, itching and redness, for pets of all ages
  • Relief from stubborn ear problem-causing microorganisms that form complex, irritating biofilms
  • Gentle formula helps relieve painful ear issues caused by resistant germs, fungi and yeast
  • Pet ear solution, no pre-cleaning of painful ears needed; safe, natural alternative to medication
  • LP3 Enzyme System to help clear ear exudate; 1% Hydrocortisone for itchy ears

Vet’s Best Ear Relief Wash

Features: This ear relief wash from Vet’s Best includes a blend of aloe, witch hazel, and other natural ingredients. It’s formulated to soothe itchy ears and reduce ear wax buildup, making it an excellent preventative measure as well. The easy-to-use applicator ensures precise application, minimizing mess.

Best for: Itchy ears due to allergens, maintenance for clean ears.

Product Review: Many users have reported noticeable improvements in their dogs’ ear conditions after using this wash. The natural ingredients are a significant selling point for pet owners concerned about chemical treatments. Additionally, the product’s ability to refresh dog ears makes it popular for regular maintenance.

Pros:
– Natural, soothing ingredients.
– Helps prevent ear infections.
– Clean and easy application.

Cons:
– May need to be used frequently for best results.
– Not as effective against severe infections.

  • COORDINATED TREATMENT - Vet's Best Dog Ear Relief Wash & Dry Cleaner Kit cleans and soothes raw, itchy, and smelly dog ears, and keeps dog's ears fresh and dry between baths.
  • FAST AND EFFECTIVE - Ear Relief Wash provides fast, effective relief from red, raw, greasy, itchy, and irritated ears.
  • LASTING RESULTS - Ear Relief Dry helps to extend the time between ear cleanings.
  • NATURAL INGREDIENTS - Both formulas contain natural ingredients in gentle and soothing combinations, including chamomile, clove oil, tea tree oil, and aloe vera.
  • MADE IN THE USA - Both formulas are alcohol-free and non-stinging.

PetHonesty Ear Infection Support for Dogs

Features: PetHonesty’s Ear Infection Support is a blend of natural ingredients, promoting ear health from the inside out. This oral supplement aims to bolster the immune system while providing essential nutrients that support ear function and hygiene.

Best for: Overall ear health and prevention of future infections.

Product Review: Pet owners appreciate that PetHonesty provides an alternative to topical treatments. Many users have reported that their dogs’ ear infections have diminished after consistent use of these chews, making them an excellent preventive option.

Pros:
– Made from natural ingredients.
– Supports overall ear health.
– Easy to administer as a treat.

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Cons:
– Requires a longer time to show effects.
– Some dogs may be picky eaters.

−$6.00
  • MEDICATED VET STRENGTH EAR DROPS - Fast-acting dog ear infection treatment drops made with pure elemental silver, 0.2% MicroSilver BG to provide antimicrobial defense against bacteria and yeast infections, and 1% Hydrocortisone to target itching and discomfort caused by inflammation.
  • ALLERGY EAR DROPS FOR DOGS - Medicated dog ear cleaner drops made with 1% Hydrocortisone to target itching, redness, and inflammation. Oticbliss Ear Drops also contain Chitosan, a natural soothing and regenerative agent that supports your pet's comfort.
  • SUPPORT HEALTHY CAT & DOG EARS - Oticbliss dog and cat ear cleaner and medicated drops help to maintain your pet's overall ear health & hygiene while targeting the effects of new or persistent ear symptoms in dogs and cats.
  • VET FORMULATED & RECOMMENDED - Vetnique cat & dog pet supplies are made in the USA from globally sourced ingredients & recommended by veterinarians worldwide! Be sure to check out our store page for more high-quality pet products.
  • VET FOUNDED. VET FORMULATED. VET RECOMMENDED - Vetnique products are made in the USA and recommended by veterinarians worldwide! Be sure to check out our store page for more high quality pet products.

Burt’s Bees for Dogs Ear Cleaner

Features: Burt’s Bees for Dogs offers a natural ear cleaner that is pH balanced for dogs. Made with apple cider vinegar and witch hazel, it helps to eliminate dirt and wax buildup while keeping the ear canal clean. The formula is soap-free and gentle enough for regular use.

Best for: Routine ear cleaning and maintenance.

Product Review: Customers rave about the effectiveness of this product at keeping ears clean without causing irritation. It’s particularly noted for its pleasant scent, which many dogs and their owners appreciate. This makes it a popular item for frequent ear maintenance.

Pros:
– Natural ingredients.
– Pleasant scent.
– Safe for regular use.

Cons:
– Not specifically designed for active infections.
– Results may vary based on individual dog needs.

−$0.79
  • DOG SKIN VS. HUMAN SKIN - Dogs' skin has a higher pH, so human skincare products can be harmful. This dog ear cleaner is specially pH balanced for dogs, reducing chances for additional irritation
  • DOG EAR CLEANING SOLUTION - This ear cleaner for dogs with naturally derived peppermint and witch hazel helps cleanse ears to reduce itching- a must-have in your puppy bathing supplies
  • HIGHEST QUALITY NATURALLY DERIVED INGREDIENTS– Safe & gentle dog ear wash with 99.7%+ natural origin formulas, formulated without chemical detergents, phthalates, parabens, or sulfates, as well as colorants and dyes
  • KIND TO THE PLANET –Our dog ear wash is packaged in 80% post-consumer recycled bottles
  • SUITABLE FOR DOGS AND PUPPIES - This dog itchy ear relief is safe for adult dogs and puppies

Waggedy Pet Organic Ear Cleaner

Features: This ear cleaner is crafted from a blend of organic ingredients, designed to remove wax buildup and soothe irritation. Its potent formulation acts against harmful bacteria and minimizes the potential for yeast infections.

Best for: Mild infections and regular cleaning.

Product Review: Users have noted that Waggedy Pet’s Organic Ear Cleaner is effective without being harsh. Many love the organic aspect, providing reassurance about what they are putting into their dog’s ears. Its overall effectiveness and gentle formulation have received numerous positive reviews.

Pros:
– Organic and natural ingredients.
– Gentle on sensitive skin.
– Highly rated for effectiveness.

Cons:
– May not provide sufficient relief for severe infections.
– Slightly more expensive compared to conventional options.

  • GENTLE DOG EAR CLEANER SOLUTION – Natural dog ear cleaner removes wax, dirt, and odor for fresh, comfortable ears. Perfect for dogs and puppies, this dog ear cleaner solution is a must in puppy essentials and everyday pet supplies.
  • EAR WASH FOR DOGS – Each 4 fl oz bottle of soothing ear drops for dogs is designed for mess-free use. Add this ear wash for dogs to your dog grooming supplies, dog bath supplies, or puppy supplies for easy ear cleaning at home.
  • PLANT-BASED & GENTLE – Our dog ear wash is made with aloe vera, witch hazel, and tea tree oil for natural care. This pet ear cleaner is plant-based, alcohol-free, and water-free, crafted as part of effective ear care products.
  • SOOTHING & EASY TO USE – Designed for everyday ear cleaning for dogs, these dog ear drops apply easily after baths or outdoor play. Prevent buildup and keep ears fresh with this essential in dog cleaning supplies and dog essentials for puppies.
  • ABOUT KIN+KIND – At kin+kind, we believe in safe and natural pet care. Our ear cleaner for dogs is carefully crafted with cruelty-free, plant-based ingredients in our USDA-certified organic facility. We proudly create eco-friendly supplies that keep pets healthy and happy.
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Zymox Otic Advanced Formula

Features: Another excellent offering from Zymox, this advanced formula is specifically designed for chronic ear infections and includes an additional component to tackle stubborn bacteria. Like its counterpart, this formula does not contain alcohol, making it safe for delicate ear tissues.

Best for: Chronic ear infections and stubborn cases.

Product Review: Pet owners dealing with recurring issues tend to find success with this product. The bacterial and fungal fighting properties are praised, alongside the formulation that promotes healing. Many users report seeing improvements within a couple of days.

Pros:
– Highly effective against stubborn infections.
– No alcohol, which prevents stinging.
– Rapid results in many cases.

Cons:
– Pricier than some other ear cleaners.
– May require multiple applications for severe issues.

  • Cat and dog ear cleaner, soothes recurrent ear issues, itching and redness, for pets of all ages
  • Relief from stubborn ear problem-causing microorganisms that form complex, irritating biofilms
  • Gentle formula helps relieve painful ear issues caused by resistant germs, fungi and yeast
  • Pet ear solution, no pre-cleaning of painful ears needed; safe, natural alternative to medication
  • LP3 Enzyme System to help clear ear exudate; 1% Hydrocortisone for itchy ears

VetIQ Ear Cleaning Solution

Features: VetIQ offers a gentle ear cleaning solution that not only cleans but also treats minor infections. This product is formulated with antibacterial and antifungal properties to assist in combatting ear issues effectively.

Best for: Maintaining a clean ear environment and treating mild infections.

Product Review: Users appreciate the solution’s dual purpose; it serves both as a cleaning agent and a treatment for minor infections. Many feel their pets enjoyed the application process, which helps reduce the stress often associated with ear cleaning.

Pros:
– Effective for both cleaning and treating.
– Gentle formula is easy on sensitive ears.
– Improved user experience during application.

Cons:
– Not for severe infections.
– Results can be slower than expected for chronic issues.

  • Cat and dog ear cleaner solution specially formulated to deodorize and clean the external ear canal
  • Ear cleaner for dogs and cats; thoroughly yet gently cleanses, dries, acidifies and deodorizes
  • Alcohol and lactic acid help dry and acidify the external ear canal while aloe softens the skin
  • Routine use promotes clean, healthy ears and aids in the prevention of external ear infections
  • Vetoquinol vet-quality ear wash is gentle enough to use regularly when bathing and grooming

Nature’s Miracle Econtinous Ear Cleaner

Features: Nature’s Miracle offers a powerful ear cleaner that works to dissolve wax buildup and eliminate odor. Enriched with natural ingredients, it aims to keep ear canals fresh and clean while providing a pleasant scent.

Best for: Routine cleaning and odor control in ears.

Product Review: Many pet owners are pleased with how effectively this product controls odors while simultaneously cleaning the ears. The natural formulation is also a favorable point for conscientious buyers. Users note that their dogs seem much more comfortable post-application.

Pros:
– Powerful odor-control properties.
– Safe, natural ingredients.
– Convenient for routine maintenance.

Cons:
– Not a treatment for infections.
– Requires frequent application to maintain results.

  • Includes one 8 oz bottle of Miracle Care Ear Cleanser for Dogs and Cats
  • Effective Cleaning: Helps clean the outer ear canal and is gentle and non-staining; Low PH of 3.0 with no antibiotics or corticosteroids; Reduces ear odor and waxy build up in your dog or cat's ears
  • How to Use: Apply 2 or 3 times per week before or after bathing, swimming, or hunting; Fill the ear canal with Ear Cleaner, gently massage the base of the ears, and use a facial tissue or cotton ball to clean the ears
  • From Nose to Toes We've Got Your Pet Covered: Our goal is to improve the human-animal bond by offering a complete line of innovative, solutions- driven products and accessories for animals, both small and large
  • Made in the USA: Proudly made at our facility located in Dayton, Ohio; our health & grooming aids have been used and recommended by top veterinarians and professional groomers for more than 40 years

Vet’s Best Ear Relief Dog Wipes

Features: These ear relief wipes are great for people who prefer a quick and easy cleaning solution. Infused with aloe and witch hazel, they provide cleaning and soothing relief simultaneously.

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Best for: Quick clean-ups and soothing irritation.

Product Review: Users love the convenience of wipes for on-the-go clean-ups. Many have noted that their dogs are calmer during the process, and the wipes are gentle enough to use frequently without irritation.

Pros:
– Convenient and easy to use.
– Gentle formula is safe for regular use.
– Effective in maintaining ear hygiene.

Cons:
– Not a substitute for deep cleaning solutions or treatment.
– May not be effective for significant buildup or infections.

  • GENTLY CLEANSING EAR WIPES: Vet’s Best Ear Relief Finger Wipes are single-use, gentle wipes designed to effectively remove dirt, waxy build-up, and debris from your dog’s ears without irritation, keeping ears clean, healthy, and comfortable.
  • SOOTHS & DEODORIZES EAR CANALS: Regular use of these gentle wipes helps safely remove build-up and discharge that cause unpleasant odors, leaving your dog’s ears feeling fresh, soothed, and deodorized for overall ear health and comfort.
  • NATURAL INGREDIENTS: Our wipes contain no parabens and are made with all-natural ingredients like witch hazel, aloe vera, and tea tree oil—providing gentle, effective cleaning and soothing care for your pet’s skin without harsh chemicals.
  • FOR REGULAR USE: Use as needed until wipes show no visible wax or buildup after use. Apply 1–2 times weekly on a routine basis to help maintain clean ears and support healthy ear hygiene for your pet with gentle, effective care.
  • EASY TO USE: Simply take one pre-moistened wipe and gently rub the accessible areas of your dog’s ears to remove dirt and wax. Designed for convenient single-use, just dispose of the wipe after use for a quick, no mess cleaning routine.

Buying Guide for Over-the-Counter Ear Infection Medicine for Dogs

Ear infections in dogs can be uncomfortable and painful. Over-the-counter (OTC) medications can provide relief, but it’s essential to choose the right product. Here’s how to select the best OTC ear infection medicine for your furry friend.

1. Understand the Types of Ear Infections

  • Bacterial Infections: Often require antibiotics; some OTC products may offer support but shouldn’t replace vet care.
  • Yeast Infections: Common in floppy-eared breeds; look for antifungal properties in medicines.
  • Allergic Reactions: Sometimes result in ear infections; antihistamines can help.

2. Consult Your Veterinarian

Before purchasing any OTC medication, consult your vet. They can help identify the cause of the infection and recommend suitable treatments. A proper diagnosis is vital, as some infections may require prescription medication.

3. Look for Key Ingredients

  • Antibiotics: Effective if a bacterial infection is suspected (consult a vet).
  • Antifungal Agents: Look for ingredients like miconazole for yeast infections.
  • Anti-inflammatory Agents: Help reduce swelling and discomfort.
  • Ceruminolytics: Help dissolve wax build-up and clean the ear canal.

4. Formulation Types

  • Ear Drops: Typically the easiest to apply; ensure the applicator is suited for small ear canals.
  • Wipes: Good for routine cleaning and maintaining ear health.
  • Sprays: Can be easier for some dogs, but ensure they don’t irritate.

5. Choose the Right Size

Consider your dog’s size and ear canal. Some products are designed specifically for small, medium, or large breeds. Always follow dosage instructions based on your dog’s weight.

6. Check for Additional Features

  • pH Balanced: Products that maintain ear canal pH can be more effective and gentler.
  • Natural Ingredients: If your dog has sensitivities, seek products with natural or hypoallergenic ingredients.
  • Added Moisturizers: Some products contain ingredients to soothe and moisturize the ear.

7. Read Reviews and Recommendations

Look for brands with positive reviews from other dog owners. Checking online forums, vet recommendations, and reputable pet product sites can provide valuable insights.

8. Consider the Price and Availability

While cheaper options can be tempting, prioritize quality and effectiveness. Compare products based on their ingredients and reviews. Some reliable brands to consider might include:

  • Vet’s Best
  • Zymox
  • Ear Cleanz

9. Watch for Reactivity

After applying any OTC medication, monitor your dog for any adverse reactions, including increased irritation, swelling, or excessive scratching. If symptoms worsen, consult your vet immediately.

10. Prevention is Key

Regular ear cleaning with gentle solutions can help prevent infections. Look for preventative ear cleaners designed to maintain ear health.

Conclusion

Selecting the right over-the-counter ear infection medicine for your dog requires careful consideration. Always seek veterinary advice when in doubt, and prioritize products that have been well-reviewed and are formulated for your dog’s specific needs. A proactive approach to ear health can reduce the likelihood of infections in the future.

William Quick
William Quick

Passionate about uncovering the best products for everyday life, I provide honest, detailed, and unbiased reviews to help you make smarter buying decisions. From tech gadgets to home essentials, I test and analyze each item thoroughly to highlight what truly matters—quality, usability, and value. Follow along for trusted insights that simplify your shopping experience and ensure you get the most out of every purchase.

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